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Scholar Results 1 - 10 of about 25 citing Payne: Haplotype tag single nucleotide polymorphism analysis of the human orthologues of.... (0.07 sec) 

Rat Models of Type 1 Diabetes: Genetics, Environment and Autoimmunity

- nas.edu [PDF] 
JP Mordes, P Poussier, AR Rossini, EP … - Animal Models of … - books.google.com
2 Animal Models of Diabetes BBDR Rats and Translational Modeling Fidelity 19 Immunological
Perturbation and Diabetes Induction in Other Rat Strains 20 TLRLigation 20 Viral Infection 21 A
Working Hypothesis of Autoimmune ...
Cited by 43 - Related articles - BL Direct - All 4 versions

IAN family critically regulates survival and development of T lymphocytes


T Nitta, M Nasreen, T Seike, A Goji, I Ohigashi, T … - biology.plosjournals.org
The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a common
ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. They have the
same chromosome number and genome ...
Cited by 33 - Related articles - Cached - BL Direct - All 12 versions

Transgenic rescue demonstrates involvement of the Ian5 gene in T cell …

- physiology.org
… , T Michalkiewicz, RA Ettinger, EA Rutledge, … - Physiological …, 2004 - Am Physiological Soc
A single point mutation in a novel immune-associated nucleotide gene 5 (Ian5) coincides with severe
T cell lymphopenia in BB rats. We used a transgenic rescue approach in lymphopenic BB-derived
congenic F344.lyp/lyp rats to ...
Cited by 28 - Related articles - All 4 versions

CBLB variants in type 1 diabetes and their genetic interaction with CTLA4

- highwire.org
R Bergholdt, C Taxvig, S Eising, J Nerup, F … - Journal of leukocyte …, 2005 - jleuk.highwire.org
Type 1 diabetes (T1D) is a multifactorial disease with genetic and environmental components
involved. Recent studies of an animal model of T1D, the Komeda diabetes-prone rat, have demonstrated
that the Casitas-B-lineage lymphoma ...
Cited by 20 - Related articles - All 6 versions

Lessons on autoimmune diabetes from animal models


Y Yang, P Santamaria - Clinical Science, 2006 - clinsci.org
Abbreviations: APC, antigen-presenting cell; BB, BioBreeding; CTLA-4, cytotoxic
T-lymphocyte-associated antigen-4; DCR3, decoy receptor 3; DC, dendritic cell; GAD65, 65 kDa
glutamic acid decarboxylase; HA, ...
Cited by 18 - Related articles - Cached - BL Direct - All 10 versions

The lymphocyte guard-IANs: regulation of lymphocyte survival by IAN/GIMAP family …

- cell.com
T Nitta, Y Takahama - Trends in immunology, 2007 - Elsevier
The life-or-death decision of immune cells makes an essential contribution to immune-system
development and the regulation of immune responses. A new family of cell-survival regulators
expressed in lymphocytes, termed ...
Cited by 14 - Related articles - All 5 versions

Nonobese diabetic mice and the genetics of diabetes susceptibility


EH Leiter - Current Diabetes Reports, 2005 - Springer
Introduction Knowledge of the genetic basis for type 1 diabetes (T1D) susceptibility in humans has
expanded from the major con- tribution of the major histocompatibility complex (MHC) class II region
(IDDM1 “superlocus,” HLA-DR, ...
Cited by 12 - Related articles - All 3 versions

[CITATION] Utility of murine models for the study of spontaneous autoimmune type 1 diabetes.


CE Mathews - Pediatric diabetes, 2005 - ncbi.nlm.nih.gov
1: Pediatr Diabetes. 2005 Sep;6(3):165-77. Utility of murine models for the study of
spontaneous autoimmune type 1 diabetes. Mathews CE. Department of Pediatrics, The University
of Pittsburgh, Pittsburgh, PA 15213, USA. cem65@pitt.edu. Publication ...
Cited by 9 - Related articles - BL Direct - All 3 versions

The human GIMAP5 gene has a common polyadenylation polymorphism …


A Hellquist, M Zucchelli, K Kivinen, U Saarialho- … - British Medical …, 2007 - jmg.bmj.com
Result: A significant increase in SLE risk associated with the most common GIMAP5 haplotype was
found (OR 1.26, 95% CI 1.02 to 1.54, p = 0.0033). In families with probands diagnosed with
trombocytopenia, the risk was ...
Cited by 11 - Related articles - BL Direct - All 8 versions

Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 …


L Cousins, M Graham, R Tooze, C Carter, JR Miller, FM … - Gastroenterology, 2006 - Elsevier
To analyze the role of the lyp gene separately from other BB genetic factors, we created congenic
rats in which the BB lyp gene was backcrossed onto the PVG-RT1 u strain. 11 The PVG-RT1 u , lyp/lyp
rat did not develop diabetes but ...
Cited by 5 - Related articles - All 14 versions


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