- ►cell.com MW Hulver, JR Berggren, MJ Carper, M … - Cell Metabolism, 2005 - Elsevier Obesity and type 2 diabetes are strongly associated with abnormal lipid
metabolism and accumulation of intramyocellular triacylglycerol, but the
underlying cause of these perturbations are yet unknown. Herein, we show ... Cited by 76 - Related articles - All 11 versions
- ►asnjournals.org K Midtvedt, J Hjelmesaeth, A Hartmann, K … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol Cardiovascular disease is a prevalent and serious complication after solid organ
transplantation. Treatment with glucocorticoids is associated with increased
risk for diabetes mellitus, insulin resistance, weight gain, ... Cited by 54 - Related articles - All 4 versions
- ►nih.gov B Ukropcova, M McNeil, O Sereda, L de Jonge … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Metabolic flexibility of skeletal muscle, that is, the preference for fat
oxidation (FOx) during fasting and for carbohydrate oxidation in response to
insulin, is decreased during insulin resistance. The aim of this study was ... Cited by 50 - Related articles - BL Direct - All 12 versions
- ►nih.gov DE Kelley - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig In order to examine the factors governing the timing and flexibility of skeletal
muscle switching between fat and carbohydrate oxidation, Ukropcova et al.
studied the effect of glucose and fatty acid availability on the preference ... Cited by 48 - Related articles - BL Direct - All 11 versions
LE Fridlyand, LH Philipson - Diabetes Obesity and Metabolism, 2006 - interscience.wiley.com The early stages of type 2 diabetes mellitus are characterized by the
development of insulin resistance (IRe) in muscle cells and adipocytes with the
concomitant loss of β-cell compensation. We have extensively reviewed the ... Cited by 45 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org ET Kase, AJ Wensaas, V Aas, K Højlund, K … - Diabetes, 2005 - Am Diabetes Assoc Liver X receptors (LXRs) are important regulators of cholesterol and lipid
metabolism and are also involved in glucose metabolism. However, the functional
role of LXRs in human skeletal muscle is at present unknown. This study ... Cited by 37 - Related articles - All 6 versions
- ►diabetesjournals.org M Gaster, AC Rustan, H Beck-Nielsen - Diabetes, 2005 - Am Diabetes Assoc We recently described a primarily reduced palmitate oxidation in myotubes
established from type 2 diabetic subjects, whereas triacylglycerol (TAG)
accumulation seemed to be adaptive. However, it is still uncertain whether ... Cited by 33 - Related articles - All 5 versions
- ►shouxi.net B Ukropcova, O Sereda, L de Jonge, I … - Diabetes, 2007 - Am Diabetes Assoc Insulin resistance is associated with metabolic inflexibility, impaired
switching of substrate oxidation from fatty acids to glucose in response to
insulin. Impaired switching to fat oxidation in response to a high-fat diet ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►endojournals.org GR Steinberg, AJ McAinch, MB Chen, PE O' … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Results: We demonstrate that leptin stimulates AMPK activity and increases AMPK
Thr172 and acetyl-CoA carboxylase-ß Ser222 phosphorylation and fatty acid
oxidation in lean myotubes but that in obese subjects leptin-dependent AMPK ... Cited by 29 - Related articles - BL Direct - All 4 versions
