D Eberle, B Hegarty, P Bossard, P Ferre, F Foufelle - Biochimie, 2004 - Elsevier Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid homeostasis by controlling the expression of a range of enzymes required for endogenous
cholesterol, fatty acid (FA), triacylglycerol and phospholipid synthesis. The three SREBP ... Cited by 186 - Related articles - All 3 versions
H Basciano, L Federico, K Adeli - Nutrition & Metabolism, 2005 - biomedcentral.com Obesity and type 2 diabetes are occurring at epidemic rates in the United States and many parts
of the world. The "obesity epidemic" appears to have emerged largely from changes in our diet
and reduced physical activity. An important but not well-appreciated dietary change has ... Cited by 123 - Related articles - Cached - All 13 versions
W Zhang, S Patil, B Chauhan, S Guo, DR Powell, J … - Journal of Biological …, 2006 - ASBMB Page 1. 1 FOXO1 REGULATES MULTIPLE METABOLIC PATHWAYS IN THE LIVER: EFFECTS
ON GLUCONEOGENIC, GLYCOLYTIC AND LIPOGENIC GENE EXPRESSION Wenwei Zhang
1,2 , Sandip Patil 1,2 , Balwant Chauhan 1,2 , Shaodong Guo 1,2 , David R. Powell 3 , ... Cited by 102 - Related articles - BL Direct - All 5 versions
- ►biologists.org H Wang, G Kouri, CB Wollheim - Journal of cell science, 2005 - jcs.biologists.org The reduction in insulin secretory capacity and ß-cell mass observed in type 2 diabetes is thought
to be caused by glucolipotoxicity secondary to hyperglycemia and hyperlipidemia. Our aim in
this study was to elucidate the underlying molecular mechanisms. We found a strong ... Cited by 104 - Related articles - BL Direct - All 7 versions
- ►nih.gov K Nagashima, C Lopez, D Donovan, C … - Journal of Clinical …, 2005 - Am Soc Clin Investig Elevated plasma levels of VLDL triglycerides (TGs) are characteristic of patients with type 2 diabetes
mellitus (T2DM) and are associated with increased production rates (PRs) of VLDL TGs and
apoB. Lipoprotein lipase–mediated (LPL-mediated) lipolysis of VLDL TGs may also be ... Cited by 89 - Related articles - All 8 versions
A Takahashi, K Motomura, T Kato, T Yoshikawa, Y … - Diabetes, 2005 - Am Diabetes Assoc Influx of excess fatty acids and the resultant accumulation of intracellular triglycerides are linked
to impaired insulin secretion and action in the pathogenesis of type 2 diabetes. Sterol regulatory
element-binding protein (SREBP)-1c is a transcription factor that controls cellular ... Cited by 43 - Related articles - All 5 versions
T Matsuzaka, H Shimano, N Yahagi, T Kato, … - Nature …, 2007 - basicmed.med.ncku.edu.tw Insulin resistance is often associated with obesity and can precipitate type 2 diabetes. To
date, most known approaches that improve insulin resistance must be preceded by the amelioration
of obesity and hepatosteatosis. Here, we show that this provision is not mandatory; insulin ... Cited by 39 - Related articles - View as HTML - BL Direct - All 12 versions
Y Nakagawa, H Shimano, T Yoshikawa, T Ide, M … - Nature medicine, 2006 - plaza.umin.ac.jp Using an expression cloning strategy, we have identified TFE3, a basic helix-loop-helix
protein, as a transactivator of metabolic genes that are regulated through an E-box in their
promoters. Adenovirus-mediated expression of TFE3 in hepatocytes in culture and in vivo ... Cited by 29 - Related articles - BL Direct - All 9 versions
- ►daegu.ac.kr [PDF] MO Weickert, AFH Pfeiffer - Diabetologia, 2006 - Springer Abstract Fatty liver and hepatic triglyceride accumulation are strongly associated with
obesity, insulin resistance and type 2 diabetes, and are subject to nutritional influences. Hepatic
regulation of glucose and lipid homeostasis is influenced by a complex system of ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►cnfindpark.cn KL Stanhope, SC Griffen, BR Bair, MM … - American Journal of …, 2008 - ajcn.cnfindpark.cn 2 Supported in part with funding from Pepsico, Inc. The project also received support from the
UC Davis Clinical and Translational Science Center (grant UL1 RR024146) and the US Department
of Agriculture. PJH's laboratory also receives support from NIH grants R01 HL075675, ... Cited by 25 - Related articles - BL Direct - All 14 versions
