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Scholar Results 1 - 10 of about 32 citing Christoffolete: Mice with targeted disruption of the Dio2 gene have cold-induced overexpression.... (0.10 sec) 

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation


M Watanabe, SM Houten, C Mataki, MA … - Nature, 2006 - nature.com
While bile acids (BAs) have long been known to be essential in dietary lipid
absorption and cholesterol catabolism, in recent years an important role for BAs
as signalling molecules has emerged. BAs activate mitogen-activated protein ...
Cited by 161 - Related articles - BL Direct - All 8 versions

Selenium, the thyroid, and the endocrine system

- endojournals.org
J Kohrle, F Jakob, B Contempre, JE Dumont - Endocrine reviews, 2005 - Endocrine Soc
Recent identification of new selenocysteine-containing proteins has revealed
relationships between the two trace elements selenium (Se) and iodine and the
hormone network. Several selenoproteins participate in the protection of ...
Cited by 102 - Related articles - BL Direct - All 5 versions

Deiodinases: implications of the local control of thyroid hormone action

- nih.gov
AC Bianco, BW Kim - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
The deiodinases activate or inactivate thyroid hormone, and their importance in
thyroid hormone homeostasis has become increasingly clear with the availability
of deiodinase-deficient animals. At the same time, heightened interest in ...
Cited by 97 - Related articles - BL Direct - All 10 versions

Insights into the role of deiodinases from studies of genetically modified animals


DLS Germain, A Hernandez, MJ Schneider, … - Thyroid, 2005 - liebertonline.com
The deiodinases function at a prereceptor level in tissues to modulate the
concentrations, and thus the actions, of thyroid hormones. Although much has
been learned in the last two decades about the biochemical proper- ties and ...
Cited by 32 - Related articles - BL Direct - All 4 versions

[PDF] Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism …


AG Dulloo, M Gubler, JP Montani, J Seydoux, … - Int J Obes Relat Metab Disord, 2004 - doc.rero.ch
Life is a combustion, but how the major fuel substrates that sustain human life
compete and interact with each other for combustion has been at the epicenter of
research into the pathogenesis of insulin resistance ever since Randle ...
Cited by 24 - Related articles - View as HTML - All 5 versions

[PDF] Thyroid hormones as molecular determinants of thermogenesis


E Silvestri, L Schiavo, A Lombardi, F Goglia - Acta Physiologica Scandinavica, 2005 - schiavonutrizione.it
Abstract Thyroid hormones (TH) are major modulators of energy metabolism and
thermogenesis. It is generally believed that 3,5,3ยข-triiodo-l-thyronine (T3) is
the only active form of TH, and that most of its effects are mediated by ...
Cited by 25 - Related articles - View as HTML - BL Direct - All 5 versions

Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling

- koki.hu [PDF] 
B Gereben, AM Zavacki, S Ribich, BW Kim, … - Endocrine Reviews, 2008 - Endocrine Soc
The iodothyronine deiodinases initiate or terminate thyroid hormone action and
therefore are critical for the biological effects mediated by thyroid hormone.
Over the years, research has focused on their role in preserving serum ...
Cited by 22 - Related articles - All 5 versions

Adaptive activation of thyroid hormone and energy expenditure

- bioscirep.org [PDF] 
AC Bianco, AL Maia, WS Silva, MA … - Bioscience reports, 2005 - Springer
The mechanisms by which thyroid hormone accelerates energy expenditure are
poorly understood. In the brown adipose tissue (BAT), activation of thyroid
hormone by type 2 iodothyronine deiodinase (D2) has been known to play a ...
Cited by 18 - Related articles - BL Direct - All 5 versions

Peripheral metabolism of thyroid hormone and glucose homeostasis


A Chidakel, D Mentuccia, FS Celi - Thyroid, 2005 - liebertonline.com
Thyroid hormone action has long been recognized as an important determinant of
glucose homeostasis. Recent advances in the knowledge of the physiology of the
deiodinases indicate that through tissue-specific regula- tion of thyroid ...
Cited by 17 - Related articles - BL Direct - All 4 versions

The small polyphenolic molecule kaempferol increases cellular energy expenditure and …


WS da-Silva, JW Harney, BW Kim, J Li, SDC … - Diabetes, 2007 - Am Diabetes Assoc
Disturbances in energy homeostasis can result in obesity and other metabolic
diseases. Here we report a metabolic pathway present in normal human skeletal
muscle myoblasts that is activated by the small polyphenolic molecule ...
Cited by 17 - Related articles - BL Direct - All 5 versions


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