- ►bloodjournal.org V Sordi, ML Malosio, F Marchesi, A Mercalli, R … - Blood, 2005 - Am Soc Hematology Bone marrow–derived mesenchymal stem cells (BM-MSCs) are stromal cells with
the ability to proliferate and differentiate into many tissues. Although they
represent powerful tools for several therapeutic settings, mechanisms ... Cited by 140 - Related articles - BL Direct - All 4 versions
- ►pnas.org RH Lee, MJ Seo, RL Reger, JL Spees, AA … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences We tested the hypothesis that multipotent stromal cells from human bone marrow
(hMSCs) can provide a potential therapy for human diabetes mellitus. Severe but
nonlethal hyperglycemia was produced in NOD/scid mice with daily low doses ... Cited by 105 - Related articles - BL Direct - All 14 versions
- ►ucsd.edu [PDF] E Hao, B Tyrberg, P Itkin-Ansari, JR Lakey, … - Nature medicine, 2006 - medscape.com The nature and even existence of adult pancreatic endocrine stem or progenitor
cells is a subject of controversy in the field of beta-cell replacement for
diabetes. One place to search for such cells is in the nonendocrine ... Cited by 103 - Related articles - BL Direct - All 11 versions
M Sykes, B Nikolic - Nature, 2005 - direct-ms.org Transplantation of haematopoietic stem cells — cells capable of self renewing
and reconstituting all types of blood cell — can treat numerous lethal
diseases, including leukaemias and lymphomas. It may now be applicable for ... Cited by 100 - Related articles - View as HTML - All 6 versions
K Timper, D Seboek, M Eberhardt, P Linscheid, … - Biochemical and biophysical research communications, 2006 - Elsevier Mesenchymal stem cells (MSC) from mouse bone marrow were shown to adopt a
pancreatic endocrine phenotype in vitro and to reverse diabetes in an animal
model. MSC from human bone marrow and adipose tissue represent very similar ... Cited by 99 - Related articles - All 5 versions
KS Choi, JS Shin, JJ Lee, YS Kim, SB Kim, … - Biochemical and biophysical research communications, 2005 - Elsevier Recent reports have suggested that mesenchymal cells derived from bone marrow
may differentiate into not only mesenchymal lineage cells but also other lineage
cells. There is possibility for insulin-producing cells (IPCs) to be ... Cited by 85 - Related articles - All 6 versions
- ►neiltheise.com [PDF] MA Hussain, ND Theise - The Lancet, 2004 - Elsevier Curative therapy for diabetes mellitus mainly implies replacement of functional
insulin-producing pancreatic β cells, with pancreas or islet-cell transplants.
However, shortage of donor organs spurs research into alternative means of ... Cited by 81 - Related articles - All 8 versions
- ►alphamedpress.org M Mimeault, SK Batra - Stem Cells, 2006 - AlphaMed Press In this study, we report on recent advances on the functions of embryonic,
fetal, and adult stem cell progenitors for tissue regeneration and cancer
therapies. We describe new procedures for derivation and maturation of ... Cited by 77 - Related articles - BL Direct - All 9 versions
- ►nih.gov M Trucco - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Type 1 diabetes is the result of an autoimmune attack against the
insulin-producing β cells of the endocrine pancreas. Current treatment for
patients with type 1 diabetes typically involves a rigorous and invasive ... Cited by 69 - Related articles - All 9 versions
PA Halban - Nature cell biology, 2004 - uoguelph.ca In August 2004, the British government awarded a licence to the Newcastle
Fertility Centre for therapeutic cloning; generation of insulin-producing cells
to treat diabetes was mentioned as a major goal. Although the authorization ... Cited by 48 - Related articles - View as HTML - BL Direct - All 9 versions
