- ►diabetesjournals.org AE Kitabchi, GE Umpierrez, MB Murphy, RA … - Diabetes Care, 2006 - Am Diabetes Assoc Although the pathogenesis of DKA is better understood than that of HHS, the basic underlying
mechanism for both disorders is a reduction in the net effective action of circulating insulin
coupled with a concomitant ... Cited by 74 - Related articles - BL Direct - All 23 versions
- ►annals.org [PDF] GE Umpierrez, D Smiley, AE Kitabchi - Annals of internal medicine, 2006 - Am Coll Physicians Several investigators have reported that more than half of African- American persons with new
diagnoses of diabetic ketoacidosis have clinical, metabolic, and immunologic features of type 2
diabetes during follow-up. These ... Cited by 58 - Related articles - BL Direct - All 6 versions
C Le May, K Chu, M Hu, CS Ortega, ER … - Proceedings of the …, 2006 - National Acad Sciences In diabetes, the death of insulin-producing β-cells by apoptosis leads to insulin deficiency. The
lower prevalence of diabetes in females suggests that female sex steroids protect from β-cell
injury. Consistent with this ... Cited by 50 - Related articles - BL Direct - All 8 versions
- ►oxfordjournals.org F Mauvais-Jarvis, SB Smith, CL May, SM … - Human Molecular …, 2004 - Oxford Univ Press Ketosis-prone diabetes (KPD) is a rare form of type 2 diabetes, mostly observed in subjects of west
African origin (west Africans and African-Americans), characterized by fulminant and phasic insulin
dependence, but lacking markers of ... Cited by 36 - Related articles - BL Direct - All 5 versions
D Beran, JS Yudkin, M de Courten - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—Insulin was present in both countries in sufficient quantities, although the financial
burden for health services and patients meant that problems with supply exist. There are problems
with quantification of needs and ... Cited by 33 - Related articles - BL Direct - All 8 versions
A Balasubramanyam, G Garza, L Rodriguez, CS … - Diabetes care, 2006 - Am Diabetes Assoc OBJECTIVE—Ketosis-prone diabetes (KPD) is an emerging, heterogeneous syndrome. A sound
classification scheme for KPD is essential to guide clinical practice and pathophysiologic studies.
Four schemes have been used and are ... Cited by 34 - Related articles - BL Direct - All 6 versions
- ►temple.edu [PDF] AE Kitabchi, EA Nyenwe - Endocrinology and metabolism clinics of North …, 2006 - Elsevier Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) potentially are fatal acute
metabolic complications of diabetes [1], [2], [3], [4], [5] and [6]. DKA accounts for 8% to 29% of
all hospital admissions with a ... Cited by 21 - Related articles - All 4 versions
- ►endojournals.org E Sobngwi, JF Gautier, JP Kevorkian, JM … - Journal of Clinical …, 2005 - Endocrine Soc Objective: KPD subjects display a propensity to hyperglycemia-induced acute insulin deficiency,
suggesting that they exhibit a propensity to oxidative stress in ß-cells. The enzyme
glucose-6-phosphate dehydrogenase ... Cited by 20 - Related articles - All 5 versions
- ►endojournals.org N Rasouli, SC Elbein - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc African-American subjects often present with hyperglycemic crisis (diabetic ketoacidosis or severe
hyperglycemia), yet subsequently are treated without insulin. The pathophysiology of this unique
condition is unknown. We ... Cited by 16 - Related articles - All 5 versions
- Free from Publisher GE Umpierrez - Diabetes care, 2006 - ncbi.nlm.nih.gov 1: Diabetes Care. 2006 Dec;29(12):2755-7. Comment on: Diabetes Care. 2006 Dec;29(12):2575-
9. Ketosis-prone type 2 diabetes: time to revise the classification of diabetes. Umpierrez
GE. Publication Types: Comment; Editorial; Research Support, NIH ... Cited by 13 - Related articles - BL Direct - All 3 versions
