- ►rh.dk [PDF] LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ... Cited by 179 - Related articles - All 25 versions
- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in
the intestinal epithelial endocrine L-cells by differential processing of
proglucagon, the gene which is expressed in these cells. The current ... Cited by 119 - Related articles - BL Direct - All 5 versions
MA Nauck, JJ Meier - Regulatory peptides, 2005 - Elsevier Glucagon-like peptide 1 (GLP-1) was discovered as an insulinotropic gut hormone,
suggesting a physiological role as an incretin hormone, ie, being responsible,
in part, for the higher insulin secretory response after oral as compared ... Cited by 107 - Related articles - All 6 versions
CF Deacon, B Ahrén, JJ Holst - eid, 2004 - informahealthcare.com Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing
interest to both diabetologists and the pharmaceutical industry alike, as they
may become established as the next member of the oral antidiabetic class of ... Cited by 102 - Related articles - All 7 versions
- ►tufts.edu [PDF] LL Baggio, DJ Drucker, 2006 - Annual Reviews Type 2 diabetes is characterized by hyperglycemia resulting from insulin
resistance in the setting of inadequate β-cell compensation. Currently
available therapeutic agents lower blood glucose through multiple ... Cited by 78 - Related articles - BL Direct - All 10 versions
CF Deacon - Regulatory peptides, 2005 - Elsevier The incretin hormones, glucose-dependent insulinotropic peptide (GIP) and
glucagon-like peptide-1 (GLP-1) are secreted from endocrine cells located in the
intestinal mucosa, and act to enhance meal-induced insulin secretion. GIP ... Cited by 70 - Related articles - All 6 versions
JJ Meier, MA Nauck - Diabetes/Metabolism Reviews - interscience.wiley.com Post-translational proteolytic processing of the preproglucagon gene in the gut
results in the formation of glucagon-like peptide 1 (GLP-1). Owing to its
glucose-dependent insulinotropic effect, this hormone was postulated to ... Cited by 73 - Related articles - All 3 versions
JJ Holst, CF Deacon - Current Opinion in Pharmacology, 2004 - Elsevier Glucagon-like peptide 1 (GLP-1) is a 30 amino acid peptide secreted by
intestinal L-cells in response to meal ingestion. It functions as one of the
incretin hormones; that is, the gut hormones that enhance ... Cited by 57 - Related articles - All 2 versions
M Nauck, A Frid, K Hermansen, NS Shah, T … - Diabetes Care, 2009 - Am Diabetes Assoc RESULTS—A1C values were significantly reduced in all liraglutide groups versus
the placebo group (P < 0.0001) with mean decreases of 1.0% for 1.8 mg
liraglutide, 1.2 mg liraglutide, and glimepiride and 0.7% for 0.6 mg ... Cited by 49 - Related articles - All 4 versions
SA Hinke, K Hellemans, FC Schuit - The Journal of physiology, 2004 - Physiological Soc It is well established that the acute rise in plasma glucose and in the incretin
hormones glucose-dependent insulinotropic peptide (GIP) and glucagon-like
peptide-1 (7–36) amide (GLP-1), as occurs during a meal, is of pivotal ... Cited by 26 - Related articles - All 9 versions
