L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in the development of
diabetic retinopathy. Activity of PARP was increased in whole retina and in endothelial cells and
pericytes of diabetic rats. ... Cited by 98 - Related articles - BL Direct - All 5 versions
P Pacher, IG Obrosova, JG Mabley, C … - Current medicinal …, 2005 - pubmedcentral.nih.gov Macro- and microvascular disease are the most common causes of morbidity and mortality in patients
with diabetes mellitus. Diabetic cardiovascular dysfunction represents a problem of great clinical
importance underlying the ... Cited by 81 - Related articles - All 9 versions
IG Obrosova, P Pacher, C Szabó, Z Zsengeller, H … - Diabetes, 2005 - Am Diabetes Assoc This study evaluated the effects of aldose reductase inhibition on diabetes-induced
oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation. In animal
experiments, control and ... Cited by 73 - Related articles - All 8 versions
R Pop-Busui, A Sima, M Stevens - Diabetes/Metabolism Reviews - interscience.wiley.com This review will focus on the impact of hyperglycemia-induced oxidative stress in the development of
diabetes-related neural dysfunction. Oxidative stress occurs when the balance between the production
of reactive oxygen species (ROS) ... Cited by 42 - Related articles - BL Direct - All 3 versions
- ►inotekcorp.com [PDF] F Li, C Szabo, P Pacher, GJ Southan, OI Abatan, T … - Diabetologia, 2004 - Springer Aims/hypothesis. Poly(ADP-ribose) polymerase acti- vation depletes NAD + and high-energy phosphates,
activates protein kinase C, and affects gene expression in various tissues. This study was designed
to charac- terise the effects of ... Cited by 38 - Related articles - BL Direct - All 11 versions
- ►nih.gov P Pacher, C Szabó - Antioxidants & redox signaling, 2005 - liebertonline.com Hyperglycemia-induced overproduction of superoxide by mitochondrial electron-transport chain
triggers several pathways of injury involved in the pathogenesis of diabetic complications [protein
kinase C (PKC), hexosamine and ... Cited by 38 - Related articles - BL Direct - All 6 versions
IG Obrosova, AG Minchenko, RN Frank, GM … - International journal of …, 2004 - inotekcorp.com INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 14: 55-64, 2004 Poly(ADP-ribose) polymerase inhibitors
counteract diabetes» and hypoxia-induced retinal vascular endothelial growth factor overexpression
IRINA G. OBROSOVA1, ALEXANDER G. ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►aspetjournals.org CY Xiao, M Chen, Z Zsengeller, C Szabo - Journal of Pharmacology and …, 2004 - ASPET Activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP)-1 by oxidant-mediated DNA damage
is an important pathway of cell dysfunction and tissue injury during myocardial infarction. Because
diabetes mellitus can substantially ... Cited by 37 - Related articles - BL Direct - All 8 versions
IG Obrosova, VR Drel, P Pacher, O Ilnytska, ZQ Wang, … - Diabetes, 2005 - Am Diabetes Assoc Poly(ADP-ribose) polymerase (PARP) activation, an important factor in the pathogenesis of diabetes
complications, is considered a downstream effector of oxidative-nitrosative stress. However, some
recent findings suggest that it is ... Cited by 38 - Related articles - BL Direct - All 11 versions
