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Scholar Results 1 - 10 of about 33 citing Valencia: Divergent pathways of gene expression are activated by the RAGE ligands S100b and AGE-BSA. (0.11 sec) 

S100 proteins expressed in phagocytes: a novel group of damage-associated …

- jleukbio.org
D Foell, H Wittkowski, T Vogl, J … - Journal of leukocyte …, 2007 - Soc Leukocyte Biology
Damage-associated molecular pattern (DAMP) molecules have been introduced as important
proinflammatory factors of innate immunity. One example known for many years to be expressed
in cells of myeloid origin are phagocytic S100 proteins, which mediate inflammatory ...
Cited by 88 - Related articles - BL Direct - All 8 versions

Advanced glycation endproducts: what is their relevance to diabetic complications? …

- critcaremed.org
N Ahmed, PJ Thornalley - Diabetes, Obesity & Metabolism, 2007 - pt.wkhealth.com
Glycation is a major cause of spontaneous damage to proteins in physiological systems. This
is exacerbated in diabetes as a consequence of the increase in glucose and other saccharides
derivatives in plasma and at the sites of vascular complications. Protein damage by the ...
Cited by 64 - Related articles - All 7 versions

The role of oxidative stress in diabetic complications


DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer
The morbidity and mortality associated with diabetes is the result of the myriad complications
related to the disease. One of the most explored hypotheses to explain the onset of complications
is a hyperglycemia-induced increase in oxidative stress. Reactive oxygen species (ROS) ...
Cited by 53 - Related articles - BL Direct - All 6 versions

Glycation and carboxymethyllysine levels in skin collagen predict the risk of future …

- diabetesjournals.org
S Genuth, W Sun, P Cleary, DR Sell, W Dahms, J … - Diabetes, 2005 - Am Diabetes Assoc
Several mechanistic pathways linking hyperglycemia to diabetes complications, including glycation
of proteins and formation of advanced glycation end products (AGEs), have been proposed.
We investigated the hypothesis that skin collagen glycation and AGEs predict the risk of ...
Cited by 48 - Related articles - BL Direct - All 6 versions

Articular chondrocytes express the receptor for advanced glycation end products: …


RF Loeser, RR Yammani, CS Carlson, H … - Arthritis and …, 2005 - pubmedcentral.nih.gov
Cited by 39 - Related articles - BL Direct - All 4 versions

Increase in production of matrix metalloproteinase 13 by human articular …


RR Yammani, CS Carlson, AR Bresnick, RF … - Arthritis Care & … - interscience.wiley.com
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functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 34 - Related articles - BL Direct - All 2 versions

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation …

- ahajournals.org
JE Kanter, F Johansson, RC LeBoeuf, KE … - Circulation research, 2007 - Am Heart Assoc
It is becoming increasingly clear that suboptimal blood glucose control results in adverse effects
on large blood vessels, thereby accelerating atherosclerosis and cardiovascular disease, manifested
as myocardial infarction, stroke, and peripheral vascular disease. Cardiovascular disease ...
Cited by 33 - Related articles - All 8 versions

The role of inflammatory cytokines in endothelial dysfunction

- nih.gov
C Zhang - Basic research in cardiology, 2008 - Springer
Ischemic heart disease (IHD) is the leading health- related cause of mortality in the Western
world. Although recent trends show decreases in mortality of patients with IHD, well over 50%
of patients exhibit myocardial infarction or sudden death. A hallmark of IHD is the ...
Cited by 27 - Related articles - All 4 versions

Advanced glycation end products (AGEs) and diabetic vascular complications

- bentham.org [PDF] 
S Yamagishi, K Nakamura, T Imaizumi - Current Diabetes Reviews, 2005 - ingentaconnect.com
Abstract: Diabetic vascular complication is a leading cause of acquired blindness, end-stage
renal failure, a variety of neuropathies and accelerated atherosclerosis, which could account
for disabilities and high mortality rates in patients with diabetes. Chronic hyperglycemia is ...
Cited by 29 - Related articles - BL Direct - All 5 versions

AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 …

- physiology.org
X Gao, H Zhang, AM Schmidt, C … - American Journal of …, 2008 - Am Physiological Soc
We hypothesized that impaired nitric oxide (NO)-dependent dilation (endothelial
dysfunction) in Type 2 diabetes results, in part, from elevated production of superoxide (O 2 –
) induced by the interaction of advanced glycation end products (AGE)/receptor for AGE ( ...
Cited by 19 - Related articles - All 5 versions


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