- ►diabetesjournals.org K Susztak, AC Raff, M Schiffer, EP Böttinger - Diabetes, 2006 - Am Diabetes Assoc Diabetic nephropathy is the most common cause of end-stage renal disease in the US Recent
studies demonstrate that loss of podocytes is an early feature of diabetic nephropathy that predicts
its progressive course. Cause and consequences of podocyte loss during early diabetic ... Cited by 165 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org MD Breyer, E Bottinger, FC Brosius III, TM … - Journal of the American …, 2005 - Am Soc Nephrol Mice provide an experimental model of unparalleled flexibility for studying mammalian
diseases. Inbred strains of mice exhibit substantial differences in their susceptibility to the renal
complications of diabetes. Much remains to be established regarding the course of ... Cited by 104 - Related articles - All 6 versions
Z Qi, H Fujita, J Jin, LS Davis, Y Wang, AB Fogo, MD … - Diabetes, 2005 - Am Diabetes Assoc Differential susceptibility to diabetic nephropathy has been observed in humans, but it has not
been well defined in inbred strains of mice. The present studies characterized the severity of
diabetic nephropathy in six inbred mouse strains including C57BL/6J, DBA/2J, FVB/NJ, ... Cited by 45 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org ZT Bloomgarden - Diabetes Care, 2005 - Am Diabetes Assoc At a symposium on the development of diabetic nephropathy, Erwin Böttinger (New York,
NY) discussed the molecular pathology of diabetic nephropathy in mice and men, referring to
the growing problems of chronic kidney disease (CKD) due to diabetes. The US ... Cited by 36 - Related articles - BL Direct - All 11 versions
K Susztak, E Ciccone, P McCue, K Sharma, … - PLoS …, 2005 - medicine.plosjournals.org We found that expression of scavenger receptor CD36 coincided with proximal tubular epithelial
cell (PTEC) apoptosis and TED specifically in human DNP. High glucose stimulated cell surface
expression of CD36 in PTECs. CD36 expression was necessary and sufficient to mediate ... Cited by 36 - Related articles - Cached - BL Direct - All 19 versions
M Takemoto, L He, J Norlin, J Patrakka, Z Xiao, … - The EMBO …, 2006 - pubmedcentral.nih.gov To advance our understanding of development, function and diseases in the kidney
glomerulus, we have established and large-scale sequenced cDNA libraries from mouse glomeruli
at different stages of development, resulting in a catalogue of 6053 different genes. The ... Cited by 34 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org C Szabó, A Biser, R Benkő, E Böttinger, K Suszták - Diabetes, 2006 - Am Diabetes Assoc The activation of the poly(ADP-ribose) polymerase (PARP) plays an important role in the pathophysiology
of various diseases associated with oxidative stress. We found increased amounts of
poly(ADP) ribosylated proteins in diabetic kidneys of Lepr db/db (BKsJ) mice, suggesting ... Cited by 36 - Related articles - BL Direct - All 6 versions
MP Cohen, S Chen, FN Ziyadeh, E Shea, EA Hud, GT … - Kidney international, 2005 - nature.com Albumin modified by Amadori-glucose adducts has been linked to the development of diabetic
nephropathy through its ability, independent of hyperglycemia, to activate protein kinase C-
(PKC- ), up-regulate the transforming growth factor- (TGF- ) system, and stimulate ... Cited by 35 - Related articles - BL Direct - All 4 versions
KG Ewens, RA George, K Sharma, FN Ziyadeh, RS … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic variation contributes
to risk of diabetic nephropathy. To assess the evidence for specific susceptibility genes, we used
the transmission/disequilibrium test (TDT) to analyze 115 candidate genes for linkage ... Cited by 34 - Related articles - BL Direct - All 5 versions
K Sharma, S RamachandraRao, G Qiu, … - The Journal of …, 2008 - pubmedcentral.nih.gov 1 Translational Research in Kidney Disease, Division of Nephrology, Department of
Medicine, University of California, San Diego, La Jolla, California, USA. 2 Veterans Administration
San Diego Healthcare System, La Jolla, California, USA. 3 Center for Novel Therapies in ... Cited by 40 - Related articles - BL Direct - All 8 versions
