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Scholar Results 1 - 10 of about 67 citing Sale: A genome-wide scan for type 2 diabetes in African-American families reveals evidence.... (0.06 sec) 

Impaired glucose homeostasis in transgenic mice expressing the human transient …

- nih.gov
D Ma, JPH Shield, W Dean, I Leclerc, C … - Journal of Clinical …, 2004 - Am Soc Clin Investig
Transient neonatal diabetes mellitus (TNDM) is a rare inherited diabetic syndrome apparent
in the first weeks of life and again during early adulthood. The relative contributions of reduced
islet β cell number and impaired β cell function to the observed hypoinsulinemia are ...
Cited by 59 - Related articles - BL Direct - All 10 versions

Computational disease gene identification: a concert of methods prioritizes type 2 …

- nih.gov
N Tiffin, E Adie, F Turner, HG Brunner, MA van … - Nucleic acids …, 2006 - Oxford Univ Press
Genome-wide experimental methods to identify disease genes, such as linkage analysis and
association studies, generate increasingly large candidate gene sets for which comprehensive
empirical analysis is impractical. Computational methods employ data from a variety of ...
Cited by 48 - Related articles - BL Direct - All 20 versions

Genotype-by-sex interaction in the aetiology of type 2 diabetes mellitus: support for …

- pubget.com [PDF] 
CL Avery, BI Freedman, AT Kraja, IB Borecki, MB Miller, … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis While there are sex-related differences in both the prevalence of type
2 diabetes mellitus and disease risk factors, there is only limited research on sex- specific influences
on type 2 diabetes aetiology within the same study population. Thus, we assessed ...
Cited by 27 - Related articles - BL Direct - All 5 versions

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains
differ in the response of their critical physiological functions, such as insulin sensitivity, ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Genetic factors in diabetic nephropathy

- asnjournals.org
BI Freedman, M Bostrom, P Daeihagh, DW … - Clinical Journal of the …, 2007 - Am Soc Nephrol
Several genes that predispose to type 2 diabetes have recently been identified. In addition to
the recognized and powerful effects of environmental factors, there is abundant evidence in support
of genetic susceptibility to the microvascular complication of nephropathy in individuals ...
Cited by 25 - Related articles - All 3 versions

A genome scan for ESRD in black families enriched for nondiabetic nephropathy

- asnjournals.org
BI Freedman, CD Langefeld, SS Rich, CJ … - Journal of the American …, 2004 - Am Soc Nephrol
Nephropathy is a complex disorder, with predisposition influenced by the interplay of both genetic
and environmental factors. As part of an effort to map genes that predispose to ESRD, a genome
scan was performed in 264 black pedigrees that contained 296 ESRD-affected sibling ...
Cited by 24 - Related articles - BL Direct - All 4 versions

[PDF] Nutrigenomics and nutrigenetics: the'omics' revolution in nutritional science


EC Mariman - Biotechnol Appl Biochem, 2006 - proteomics.unimaas.nl
Page 1. NUTRIGENOMICS AND NUTRIGENETICS: THE OMICS-REVOLUTION IN
NUTRITIONAL SCIENCE Running title: the omics-revolution in nutritional science
Edwin CM Mariman, PhD, Professor of Functional Genomics, ...
Cited by 21 - Related articles - View as HTML - BL Direct - All 10 versions

Linkage Analysis of Diabetes Status Among Hypertensive Families


CL Avery, BI Freedman, G Heiss, A Kraja, T Rice, D … - Diabetes, 2004 - Am Diabetes Assoc
Type 2 diabetes susceptibility is determined by multiple genetic and environmental factors.
Genome-wide linkage scans have localized common regions, possibly harboring susceptibility
genes on chromosomes 1, 2, 12, and 20. Variability in linkage findings underscores the ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Loci contributing to adult height and body mass index in African American families …


MM Sale, BI Freedman, PJ Hicks, AH … - Annals of human …, 2005 - interscience.wiley.com
Height and body mass index (BMI) have high heritability in most studies. High BMI and reduced
height are well-recognized as important risk factors for a number of cardiovascular diseases.
We investigated these phenotypes in African American families originally ascertained for ...
Cited by 18 - Related articles - BL Direct - All 3 versions

A strategy to search for common obesity and type 2 diabetes genes

- kuleuven.be [PDF] 
CC Elbers, NC Onland-Moret, L Franke, AG Niehoff, … - Trends in Endocrinology & …, 2007 - Elsevier
Worldwide, the incidence of type 2 diabetes is rising rapidly, mainly because of the increase
in the incidence of obesity, which is an important risk factor for this condition. Both obesity and
type 2 diabetes are complex genetic traits but they also share some nongenetic risk ...
Cited by 18 - Related articles - All 7 versions


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