D Eberle, B Hegarty, P Bossard, P Ferre, F … - Biochimie, 2004 - Elsevier Sterol regulatory element binding proteins (SREBPs) are a family of
transcription factors that regulate lipid homeostasis by controlling the
expression of a range of enzymes required for endogenous cholesterol, fatty ... Cited by 186 - Related articles - All 3 versions
- ►biologists.org H Wang, G Kouri, CB Wollheim - Journal of cell science, 2005 - jcs.biologists.org The reduction in insulin secretory capacity and ß-cell mass observed in type 2
diabetes is thought to be caused by glucolipotoxicity secondary to hyperglycemia
and hyperlipidemia. Our aim in this study was to elucidate the underlying ... Cited by 104 - Related articles - BL Direct - All 7 versions
- ►fasebj.org DM Mutch, W Wahli, G Williamson - The FASEB Journal, 2005 - FASEB The recognition that nutrients have the ability to interact and modulate
molecular mechanisms underlying an organism's physiological functions has
prompted a revolution in the field of nutrition. Performing ... Cited by 87 - Related articles - BL Direct - All 7 versions
P Ferre, F Foufelle - Horm Res, 2007 - content.karger.com Insulin has long-term effects on glucose and lipid metabolism through its
control on the expression of specific genes. In insulin sensitive tissues and
particularly in the liver, the transcription factor sterol regulatory ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org NR Qi, J Wang, V Zidek, V Landa, P Mlejnek, … - Hypertension, 2005 - Am Heart Assoc Fatty liver is extremely common in insulin-resistant patients with either
obesity or lipodystrophy and it has been proposed that hepatic steatosis be
considered an additional feature of the metabolic syndrome. Although ... Cited by 21 - Related articles - All 7 versions
- ►endojournals.org AM Poynten, SK Gan, AD Kriketos, LV … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Circulating lipids and tissue lipid depots predict insulin sensitivity.
Associations between fat oxidation and insulin sensitivity are variable. We
examined whether circulating lipids and fat oxidation independently ... Cited by 11 - Related articles - All 4 versions
- ►nih.gov YS Lee, DH Sohn, D Han, HW Lee, RH Seong … - Molecular and cellular biology, 2007 - Am Soc Microbiol Insulin plays a critical role in whole-body energy homeostasis by regulating
lipid and glucose metabolism. In fat and liver tissues, ADD1/SREBP1c is a key
transcription factor to mediate insulin-dependent regulation of gene ... Cited by 11 - Related articles - BL Direct - All 12 versions
- ►nih.gov AH Harding, RJF Loos, J Luan, SO'Rahilly, NJ … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis The sterol regulatory element-binding fac- tor
(SREBF)-1c is a transcription factor involved in the regulation of lipid and
glucose metabolism. We have previously found evidence that a common SREBF1c ... Cited by 9 - Related articles - All 11 versions
TK Felder, H Oberkofler, R Weitgasser, V … - International Journal of Obesity, 2006 - nature.com The sterol regulatory element-binding protein-1c (SREBP-1c) is a transcription
factor involved in the regulation of lipid and glucose metabolism and has been
implicated in the pathophysiology of type 2 diabetes mellitus (T2DM). Cited by 8 - Related articles - BL Direct - All 4 versions
R Laaksonen, KM Thelen, H Päivä, J … - Atherosclerosis, 2006 - Elsevier Sterol regulatory element binding proteins-1 and -2 (SREBPs) are transcription
factors controlling lipid homeostasis in human cells. The G-allele carriers of
the SREBF-1 gene C–G polymorphism in exon 18c and coding for glycine at ... Cited by 8 - Related articles - All 14 versions
