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Scholar Results 1 - 10 of about 21 citing Eftychi: Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the.... (0.12 sec) 

Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on …

- endojournals.org
SK Hansen, EMD Nielsen, J Ek, G Andersen, C … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
The separate and combined effects of the PPARG Pro 12 Ala polymorphism and the
KCNJ11 Glu 23 Lys polymorphisms on risk of type 2 diabetes were investigated in
relatively large-scale, case-control studies. Separate effects of the ...
Cited by 25 - Related articles - All 5 versions

Activating mutations in the KCNJ11 gene encoding the ATP-sensitive K+ channel subunit Kir6. …

- diabetesjournals.org
EL Edghill, AL Gloyn, KM Gillespie, AP … - Diabetes, 2004 - Am Diabetes Assoc
We have recently shown that permanent neonatal diabetes can be caused by
activating mutations in KCNJ11 that encode the Kir6.2 subunit of the ß-cell
ATP-sensitive K + channel. Some of these patients were diagnosed after 3 ...
Cited by 25 - Related articles - BL Direct - All 4 versions

[PDF] Mouse models of type 1 and type 2 diabetes derived from the same closed colony: genetic …


H Ikegami, T Fujisawa, T Ogihara - ILAR JOURNAL., 2004 - dels.nas.edu
Except for rare subtypes of diabetes, both type 1 and type 2 diabetes are
multifactorial diseases in which genetic factors consisting of multiple
susceptibility genes and environmen- tal factors contribute to the disease ...
Cited by 14 - Related articles - View as HTML - BL Direct - All 2 versions

Candidate gene association study of insulin signaling genes and Alzheimers disease: …


G Hamilton, P Proitsi, L Jehu, A Morgan, J … - AMERICAN JOURNAL OF MEDICAL GENETICS. PART …, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 12 - Related articles - BL Direct - All 3 versions

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with …

- endojournals.org [PDF] 
S Noso, H Ikegami, T Fujisawa, Y Kawabata, K … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Page 1. - 1 - Full title: Association of small ubiquitin-like modifier 4
(SUMO4) variant, located in IDDM5 locus, with type 2 diabetes ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Mouse Models and the Genetics of Diabetes


EH Leiter, CH Lee - Diabetes, 2005 - Am Diabetes Assoc
In humans, both type 1 and type 2 diabetes exemplify genetically heterogeneous
complex diseases in which epigenetic factors contribute to underlying genetic
susceptibility. Extended human pedigrees often show inheritance of both ...
Cited by 10 - Related articles - BL Direct - All 6 versions

IRS1, KCNJ11, PPARgamma2 and HNF-1alpha: do amino acid polymorphisms in these …


A Johansen, DP Jensen, R Bergholdt, HB … - Diabetes, Obesity and Metabolism, 2006 - interscience.wiley.com
Aims: Type 1 diabetes mellitus (T1DM) is a chronic disorder primarily triggered
by environmental and immunological factors in genetically susceptible
individuals. Despite the fact that there are indications of common ...
Cited by 9 - Related articles - All 2 versions

Co-localisation of the Kir6. 2/SUR1 channel complex with glucagon-like peptide-1 and …

- eje-online.org
LB Nielsen, KB Ploug, P Swift, C Orskov, I … - European Journal of Endocrinology, 2007 - EFES
Objective: The ATP-dependent K + -channel (K ATP ) is critical for glucose
sensing and normal glucagon and insulin secretion from pancreatic endocrine -
and ß-cells. Gastrointestinal endocrine L- and K-cells are also ...
Cited by 8 - Related articles - BL Direct - All 6 versions

The PPARγ2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes …


A Jorsal, L Tarnow, M Lajer, J Ek, T Hansen, … - Molecular genetics and metabolism, 2008 - Elsevier
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2
gene is suggested to associate with diabetic nephropathy and cardiovascular
disease in type 2 diabetes. The aim of this study was to investigate the ...
Cited by 6 - Related articles - All 3 versions

No association of multiple type 2 diabetes loci with type 1 diabetes

- nih.gov
SM Raj, JMM Howson, NM Walker, JD Cooper, … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis We used recently confirmed type 2 diabe- tes gene
regions to investigate the genetic relationship between type 1 and type 2
diabetes, in an average of 7,606 type 1 diabetic individuals and 8,218 ...
Cited by 1 - Related articles - All 4 versions


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