- ►shouxi.net B Guigas, L Bertrand, N Taleux, M Foretz, N … - Diabetes, 2006 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) controls glucose uptake and glycolysis in
muscle. Little is known about its role in liver glucose uptake, which is
controlled by glucokinase. We report here that ... Cited by 44 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org VA Payne, C Arden, C Wu, AJ Lange, L Agius - Diabetes, 2005 - Am Diabetes Assoc Hepatic glucokinase is regulated by a 68-kDa regulatory protein (GKRP) that is
both an inhibitor and nuclear receptor for glucokinase. We tested the role of
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK2) in regulating ... Cited by 29 - Related articles - All 5 versions
XJ Wang, M Chamberlain, O Vassieva, CJ … - Biochemical Journal, 2005 - pubmedcentral.nih.gov Biochem. J. (2005) 388, 857–867 (Printed in Great Britain) ... Relationship
between hepatic phenotype and changes in gene expression ... Xiu Jun WANG*,
Mark CHAMBERLAIN*, Olga VASSIEVA†, Colin J. HENDERSON* and C. Roland WOLF* Cited by 19 - Related articles - All 8 versions
T Koeck, D Stuehr, K Aulak - Biochemical Society Transactions, 2005 - bst.portlandpress.com The conditions of the cellular microenvironment in complex multicellular
organisms fluctuate, enforcing permanent adaptation of cells at multiple
regulatory levels. Covalent post-translational modifications of proteins ... Cited by 13 - Related articles - Cached - BL Direct - All 11 versions
CM García-Herrero, M Galan, O Vincent, B … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Glucokinase (GCK) acts as a glucose sensor in the
pancreatic beta cell and regulates insulin secretion. In the gene encoding GCK
the heterozygous mutations that result in enzyme inactivation cause MODY2. ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►ncl.ac.uk [PDF] C Arden, S Baltrusch, L Agius - FEBS letters, 2006 - Elsevier The association of glucokinase with liver mitochondria has been reported [Danial
et al. (2003) BAD and glucokinase reside in a mitochondrial complex that
integrates glycolysis and apoptosis. Nature 424, 952–956]. We confirmed ... Cited by 10 - Related articles - All 12 versions
- ►shouxi.net S Baltrusch, F Francini, S Lenzen, M Tiedge - Diabetes, 2005 - Am Diabetes Assoc The glucokinase regulatory protein (GRP) plays a pivotal role in the regulation
of metabolic flux in liver by the glucose-phosphorylating enzyme glucokinase.
Random peptide phage display library screening for binding partners of GRP ... Cited by 9 - Related articles - BL Direct - All 5 versions
M Galán, O Vincent, I Roncero, S Azriel, P … - Biochemical Journal, 2006 - pubmedcentral.nih.gov Glucokinase acts as the pancreatic glucose sensor and plays a critical role in
the regulation of insulin secretion by the β-cell. Heterozygous mutations in
the glucokinase-encoding GCK gene, which result in a reduction of the ... Cited by 10 - Related articles - BL Direct - All 10 versions
- ►endojournals.org S Baltrusch, S Langer, L Massa, M Tiedge, S … - Endocrinology, 2006 - Endocrine Soc The glucose sensor enzyme glucokinase plays a pivotal role in the regulation of
glucose-induced insulin secretion in pancreatic ß-cells. Activation of
glucokinase represents a promising concept for the treatment of type 2 ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►physiology.org VA Payne, C Arden, AJ Lange, L Agius - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc The insulin-resistant Zucker fa/fa rat has elevated hepatic glycolysis and
activities of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2
(PFK2). The latter catalyzes the formation and degradation of fructose-2,6- ... Cited by 6 - Related articles - BL Direct - All 5 versions
