- ►cell.com A Barthel, D Schmoll, TG Unterman - Trends in Endocrinology & Metabolism, 2005 - Elsevier There is increasing evidence that Forkhead box 'Other' (FoxO) proteins, a subgroup of the Forkhead
transcription factor family, have an important role in mediating the effects of insulin and growth
factors on diverse physiological functions, including cell proliferation, apoptosis and ... Cited by 134 - Related articles - All 9 versions
- ►nih.gov AR Wende, JM Huss, PJ Schaeffer, V Giguere … - Molecular and Cellular …, 2005 - Am Soc Microbiol The transcriptional coactivator PGC-1 is a key regulator of energy metabolism, yet little is known
about its role in control of substrate selection. We found that physiological stimuli known to induce
PGC-1 expression in skeletal muscle coordinately upregulate the expression of pyruvate ... Cited by 93 - Related articles - All 5 versions
- ►fasebj.org JA Timmons, O Larsson, E Jansson, H Fischer, T … - The FASEB Journal, 2005 - FASEB Global gene expression profiling is used to generate novel insight into a variety of disease
states. Such studies yield a bewildering number of data points, making it a challenge to validate
which genes specifically contribute to a disease phenotype. Aerobic exercise training ... Cited by 50 - Related articles - All 8 versions
LP van der Heide, MP Smidt - Trends in Biochemical Sciences, 2005 - Elsevier Forkhead box, class O (FoxO) transcription factors are inhibited by insulin-induced FoxO
phosphorylation. Recently, acetylation of FoxO factors by calcium response element-binding
(CREB)-binding protein (CBP) and/or p300 has been identified as a novel regulatory ... Cited by 44 - Related articles - All 6 versions
- ►rupress.org F Fallarino, R Bianchi, C Orabona, C Vacca, … - Journal of Experimental …, 2004 - jem.rupress.org Prediabetes and diabetes in nonobese diabetic (NOD) mice have been targeted by a variety
of immunotherapies, including the use of a soluble form of cytotoxic T lymphocyte antigen 4
(CTLA-4) and interferon (IFN)- . The cytokine, however, fails to activate tolerogenic ... Cited by 45 - Related articles - BL Direct - All 5 versions
- ►jbc.org CC Bastie, Z Nahle, T McLoughlin, K Esser, W … - Journal of Biological …, 2005 - ASBMB Emerging evidence documents a key function for the forkhead transcription factor FoxO1 in cellular
metabolism. Here, we investigate the role of FoxO1 in the regulation of fatty acid (FA) metabolism
in muscle cells. C2C12 cells expressing an inducible construct with either wild type ... Cited by 39 - Related articles - All 7 versions
- ►nih.gov LH Kasper, T Fukuyama, MA Biesen, F … - Molecular and cellular …, 2006 - Am Soc Microbiol The global transcriptional coactivators CREB-binding protein (CBP) and the closely related p300
interact with over 312 proteins, making them among the most heavily connected hubs in the known
mammalian protein-protein interactome. It is largely uncertain, however, if these ... Cited by 35 - Related articles - BL Direct - All 13 versions
- ►physiology.org B Gershman, O Puig, L Hang, RM Peitzsch, … - Physiological …, 2007 - Am Physiological Soc A high-resolution time series of transcript abundance was generated to describe global expression
dynamics in response to nutrition in Drosophila. Nonparametric change-point statistics revealed
that within 7 h of feeding upon yeast, transcript levels changed significantly for 3,500 ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] DL Allen, TG Unterman - American Journal of Physiology- Cell …, 2006 - Am Physiological Soc Page 1. Myostatin and FoxO1 1 Regulation of Myostatin Expression and Myoblast Differentiation
by FoxO and SMAD Transcription Factors David L. Allen 1 * and Terry G. Unterman 2, 3, 4 1
Department of Integrative Physiology, University of Colorado, Boulder ... Cited by 38 - Related articles - BL Direct - All 4 versions