- ►umflint.edu [PDF] MV Kokoeva, H Yin, JS Flier - Science, 2005 - sciencemag.org Ciliary neurotrophic factor (CNTF) induces weight loss in obese rodents and humans, and for
reasons that are not understood, its effects persist after the cessation of treatment. Here we demonstrate
that centrally administered CNTF induces cell proliferation in feeding centers of the ... Cited by 126 - Related articles - BL Direct - All 12 versions
JK Elmquist, R Coppari, N Balthasar, M … - Journal of …, 2005 - interscience.wiley.com The past decade has greatly increased our understanding and appreciation of the ability of the
central nervous system (CNS) to regulate food intake and body weight. This was spearheaded
by the discovery of key molecules regulating body weight homeostasis. It is now also ... Cited by 73 - Related articles - BL Direct - All 4 versions
C Sachot, S Poole, GN Luheshi - The Journal of Physiology, 2004 - Physiological Soc Anorexia and fever are important features of the host's response to inflammation that can be
triggered by the bacterial endotoxin lipopolysaccharide (LPS) and the appetite suppressant
leptin. Previous studies have demonstrated that LPS induces leptin synthesis and ... Cited by 43 - Related articles - All 7 versions
- ►diabetesjournals.org M López, CJ Lelliott, S Tovar, W Kimber, R Gallego, S … - Diabetes, 2006 - Am Diabetes Assoc Fatty acid metabolism in the hypothalamus has recently been shown to regulate feeding. The
selective estrogen receptor modulator tamoxifen (TMX) exerts a potent anorectic effect.
Here, we show that the anorectic effect of TMX is associated with the accumulation of ... Cited by 38 - Related articles - BL Direct - All 8 versions
- ►endojournals.org GR Steinberg, MJ Watt, BC Fam, J Proietto, S … - Endocrinology, 2006 - Endocrine Soc We examined the actions of a second-generation ciliary neurotrophic factor analog (CNTF Ax15
) on AMP-activated protein kinase (AMPK), a known regulator of food intake. Unlike leptin CNTF
Ax15 has been shown to reduce food intake in obese rodents and humans. ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►cjb.net M Fry, PM Smith, TD Hoyda, M Duncan, RS … - Journal of …, 2006 - neuro.cjb.net Adiponectin is an adipocyte-derived peptide hormone involved in energy homeostasis and the
pathogenesis of obesity, including hypertension. Area postrema (AP) lacks a blood–brain barrier
and is a critical homeostatic integration center for humoral and neural signals. Here we ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►uchile.cl [PDF] C Vergara, B Ramirez - Brain Research Reviews, 2004 - Elsevier CNTF is a member of a group of signaling molecules, the cytokines, that act as chemical communicators
between cells by binding to a complex of proteins in the target tissues. This complex is formed
by a specific alpha-receptor subunit and one or more beta subunits that are coupled to ... Cited by 26 - Related articles - All 4 versions
- ►nih.gov MA Febbraio - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Obesity and its related cluster of pathophysiologic conditions including insulin resistance, glucose
intolerance, dyslipidemia, and hypertension are recognized as growing threats to world
health. It is now estimated that 10% of the world's population is overweight or obese. As a ... Cited by 26 - Related articles - BL Direct - All 7 versions
JRS Arch - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press The regulation of energy balance is complex and, in man, imprecise. Nevertheless, in many individuals
intake and expenditure are balanced with <1% error with little or no conscious effect. Essential
components of such a regulatory system are signals, leptin and insulin, that reflect the ... Cited by 22 - Related articles - All 5 versions
