KAM Jandeleit-Dahm, C Tikellis, CM Reid, CI … - Journal of hypertension, 2005 - journals.lww.com Recent trials have suggested that inhibitors of the renin-angiotensin system
(RAS), such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin II
receptor blockers (ARBs), may reduce the incidence of new-onset diabetes in ... Cited by 154 - Related articles - All 6 versions
- ►critcaremed.com M Burnier, A Zanchi - Journal of hypertension, 2006 - journals.lww.com Diabetes (particularly type 2 diabetes) represents a global health problem of
epidemic proportions. Individuals with diabetes are not only more likely to
develop hypertension, dyslipidemia, and obesity, but are also at a ... Cited by 60 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org KY Chu, T Lau, PO Carlsson, PS Leung - Diabetes, 2006 - Am Diabetes Assoc We identified an angiotensin-generating system in pancreatic islets and found
that exogenously administered angiotensin II, after binding to its receptors
(angiotensin II type 1 receptor [AT1R]), inhibits insulin release in a ... Cited by 55 - Related articles - BL Direct - All 9 versions
ME Cooper - American Journal of Hypertension, 2004 - Elsevier Clinical trials have demonstrated the benefit of blood pressure (BP) reduction
in reducing the risk of cardiovascular and renal complications in patients with
diabetes mellitus. Incorporation of agents that inhibit the ... Cited by 48 - Related articles - All 7 versions
M Nakayama, T Inoguchi, T Sonta, Y Maeda, … - Biochemical and Biophysical Research …, 2005 - Elsevier This study was undertaken to reveal the role of NAD(P)H oxidase in increased
oxidative stress in islets of Type 2 diabetes. Immunostaining analysis showed
that staining intensities of NAD(P)H oxidase components, gp91phox and ... Cited by 40 - Related articles - All 6 versions
PS Leung, PO Carlsson - Pancreas, 2005 - journals.lww.com Supported by the Mainline Research Scheme from the Chinese University of Hong
Kong (MR00/008) and partially by the Research Grants Council of Hong Kong (CUHK
4075/00M, CUHK 4116/01M, and CUHK4364/04M), the Swedish Research Council ... Cited by 38 - Related articles - All 6 versions
- ►nih.gov PS Leung - The Journal of Physiology, 2007 - Physiological Soc The systemic renin–angiotensin system (RAS) plays an important role in
regulating blood pressure, electrolyte and fluid homeostasis. However, local
RASs also exist in diverse tissues and organs, where they play a multitude ... Cited by 33 - Related articles - BL Direct - All 11 versions
T Inoguchi, H Nawata - Current Drug Targets, 2005 - ingentaconnect.com Abstract: Both protein kinase C (PKC) activation and increased oxidative stress
have been paid attention to as important causative factors for diabetic vascular
complications. In this article, we show a PKC-dependent increase in ... Cited by 31 - Related articles - All 2 versions
MR Hayden, CS Stump, JR Sowers - Journal of the cardiometabolic syndrome, 2006 - ncbi.nlm.nih.gov The cardiometabolic syndrome is a construct associated with an increased risk of
type 2 diabetes mellitus, cardiovascular disease (coronary artery disease,
peripheral arterial disease, and stroke), chronic kidney disease, and the ... Cited by 31 - Related articles - All 2 versions
J Shao, N Iwashita, F Ikeda, T Ogihara, T … - Biochemical and biophysical research communications, 2006 - Elsevier Several epidemiological studies suggested that treatment with angiotensin II
type 1 receptor blocker (ARB) provided a risk reduction of developing type 2
diabetes. In this study, we investigated whether and how ARB treatment can ... Cited by 31 - Related articles - All 6 versions
