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Scholar Results 1 - 10 of about 25 citing Uehara: Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for.... (0.07 sec) 

Metabotropic glutamate receptors


F Ferraguti, R Shigemoto - Cell and tissue research, 2006 - Springer
Abstract Metabotropic glutamate receptors (mGlus) are a family of
G-protein-coupled receptors activated by the neurotransmitter glutamate.
Molecular cloning has revealed eight different subtypes (mGlu1-8) with ...
Cited by 60 - Related articles - BL Direct - All 4 versions

{alpha}-Cells of the endocrine pancreas: 35 years of research but the enigma remains

- endojournals.org
J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc
Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ...
Cited by 60 - Related articles - BL Direct - All 4 versions

Glutamatergic chemical transmission: look! Here, there, and anywhere


Y Moriyama, A Yamamoto - Journal of Biochemistry, 2004 - Jpn Biochemical Soc
Vesicular glutamate transporter (VGLUT) is responsible for the active transport
of L-glutamate in synaptic vesicles and thus plays an essential role in the
glutamatergic chemical transmission in the central nervous system. VGLUT ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Insulin regulates islet {alpha}-cell function by reducing KATP channel sensitivity to adenosine …


YM Leung, I Ahmed, L Sheu, X Gao, M Hara, … - Endocrinology, 2006 - Endocrine Soc
Glucose regulates pancreatic islet -cell glucagon secretion directly by its
metabolism to generate ATP in -cells, and indirectly via stimulation of
paracrine release of ß-cell secretory products, particularly insulin. How ...
Cited by 20 - Related articles - All 4 versions

Secretion of L-glutamate from osteoclasts through transcytosis


R Morimoto, S Uehara, S Yatsushiro, N Juge … - The EMBO Journal, 2006 - pubmedcentral.nih.gov
Osteoclasts are involved in the catabolism of the bone matrix and eliminate the
resulting degradation products through transcytosis, but the molecular mechanism
and regulation of transcytosis remain poorly understood. Upon ...
Cited by 16 - Related articles - BL Direct - All 8 versions

Zinc, not insulin, regulates the rat α-cell response to hypoglycemia in vivo

- shouxi.net
H Zhou, T Zhang, JS Harmon, J Bryan, RP … - Diabetes, 2007 - Am Diabetes Assoc
The intraislet insulin hypothesis proposes that the decrement in β-cell insulin
secretion during hypoglycemia provides an activation signal for α-cells to
release glucagon. A more recent hypothesis proposes that zinc atoms ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Gamma-aminobutyric acid up-and downregulates insulin secretion from beta cells in concert …


H Dong, M Kumar, Y Zhang, A Gyulkhandanyan … - Diabetologia, 2006 - Springer
Gamma-aminobutyric acid up- and downregulates insulin ... Received: 18 August
2005 / Accepted: 1 November 2005 / Published online: 31 January 2006 #
Springer-Verlag 2006 ... Abstract Aims/hypothesis: The role of ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors

- aspetjournals.org
M Storto, L Capobianco, G Battaglia, G … - Molecular pharmacology, 2006 - ASPET
Recent evidence suggests that metabotropic glutamate (mGlu) receptors are
involved in the regulation of hormone secretion in the endocrine pancreas. We
report here that endogenous activation of mGlu5 receptors is required for ...
Cited by 10 - Related articles - BL Direct - All 6 versions

A Novel Variant of Ionotropic Glutamate Receptor Regulates Somatostatin Secretion From δ- …


A Muroyama, S Uehara, S Yatsushiro, N … - Diabetes, 2004 - Am Diabetes Assoc
Many metabolic factors affect the secretion of insulin from β-cells and
glucagon from α-cells of the islets of Langerhans to regulate blood glucose.
Somatostatin from δ-cells, considered a local inhibitor of islet function, ...
Cited by 9 - Related articles - BL Direct - All 7 versions

Physiology of the pancreatic {alpha}-cell and glucagon secretion: role in glucose …

- endocrinology-journals.org
I Quesada, E Tuduri, C Ripoll, A Nadal - Journal of Endocrinology, 2008 - Soc Endocrinology
The secretion of glucagon by pancreatic -cells plays a critical role in the
regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes
insulin actions by stimulating hepatic glucose synthesis and mobilization, ...
Cited by 8 - Related articles - All 3 versions


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