JN Feige, L Gelman, L Michalik, B Desvergne, W … - Progress in Lipid …, 2006 - Elsevier Peroxisome proliferator-activated receptors (PPARs) compose a family of three nuclear receptors
which act as lipid sensors to modulate gene expression. As such, PPARs are implicated in major
metabolic and inflammatory regulations with far-reaching medical consequences, as well ... Cited by 158 - Related articles - All 2 versions
A Koerner, J Kratzsch, W Kiess - … Practice & Research Clinical Endocrinology & …, 2005 - Elsevier With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has
been extended to the secretory products of adipocytes, since they are increasingly shown to
affect several aspects in the pathogenesis of obesity-related diseases. The cloning of the ... Cited by 136 - Related articles - All 12 versions
- ►nih.gov BHJ Chang, L Li, A Paul, S Taniguchi, V … - Molecular and Cellular …, 2006 - Am Soc Microbiol Adipose differentiation-related protein (ADFP; also known as ADRP or adipophilin), is a lipid
droplet (LD) protein found in most cells and tissues. ADFP expression is strongly induced in cells
with increased lipid load. We have inactivated the Adfp gene in mice to better understand ... Cited by 76 - Related articles - BL Direct - All 7 versions
NE Wolins, DL Brasaemle, PE Bickel - FEBS letters, 2006 - Elsevier Humans have evolved mechanisms of efficient fat storage to survive famine, but these mechanisms
contribute to obesity in our current environment of plentiful food and reduced activity. Little is
known about how animals package fat within cells. Five related structural proteins serve ... Cited by 73 - Related articles - All 16 versions
GY Carmen, SM Víctor - Cellular signalling, 2006 - Elsevier Adipose tissue plays an important role providing energy to other tissues and functioning as an
energy reserve organ. The energy supply is produced by triglycerides stored in a large vacuole
representing approximately 95% of adipocyte volume. In the fasting period, triglyceride ... Cited by 67 - Related articles - All 4 versions
A Hammarstedt, V Rotter Sopasakis, S Gogg, PA … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: We examined whether short- term treatment with a thiazolidinedione
improves insulin sensitivity in non-obese but insulin-resistant subjects and whether this is associated
with an improvement in dysregulated adipose tissue (reduced expression of IRS- 1, ... Cited by 46 - Related articles - All 3 versions
- ►jbc.org Y Zuo, L Qiang, SR Farmer - Journal of Biological Chemistry, 2006 - ASBMB Studies have shown that CCAAT/enhancer-binding protein (C/EBP ) can stimulate adipogenesis
in noncommitted fibroblasts by activating expression of peroxisome proliferator-activated
receptor- (PPAR ). Other investigations have established a role for C/EBP as well as ... Cited by 35 - Related articles - BL Direct - All 5 versions
A Rudich, R Ben-Romano, S Etzion, N … - Acta Physiologica …, 2005 - interscience.wiley.com Accumulating clinical evidence now links HIV protease inhibitors (HPIs) to the pathogenesis
of insulin resistance, dyslipidaemia, lipodystrophy and atherosclerosis associated with highly
active anti-retroviral therapy. Here we briefly describe the evidence for a distinct causative ... Cited by 34 - Related articles - All 3 versions
- ►jbc.org T Yamaguchi, S Matsushita, K Motojima, F Hirose, T … - Journal of Biological …, 2006 - ASBMB Cytosolic lipid droplets (LDs) are multifunctional organelles that exist in all types of eukaryotic
cells and control lipid homeostasis. In mammalian cells LDs contain a class of proteins in their
surface layers that share a homologous sequence called the PAT domain, including ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►endojournals.org [PDF] NA Ducharme, PE Bickel - Endocrinology, 2008 - Endocrine Soc Page 1. Lipid Droplets in Lipogenesis and Lipolysis Nicole A. Ducharme and Perry E. Bickel
Center for Diabetes and Obesity Research Brown Foundation Institute of Molecular Medicine
University of Texas Health Science Center at Houston Houston, TX 77030 ... Cited by 37 - Related articles - All 3 versions
