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Scholar Results 1 - 10 of about 32 citing Mi: Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type.... (0.24 sec) 

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic …

- jimmunol.org
YG Chen, CM Choisy-Rossi, TM Holl, HD … - The Journal of Immunology, 2005 - Am Assoc Immnol
NKT cell activation by -galactosylceramide ( -GalCer) inhibits autoimmune
diabetes in NOD mice, in part by inducing recruitment to pancreatic lymph nodes
(PLNs) of mature dendritic cells (DCs) with disease-protective effects. ...
Cited by 66 - Related articles - All 5 versions

Natural killer T cells as targets for immunotherapy of autoimmune diseases


L Van Kaer - Immunology and cell biology, 2004 - nature.com
CD1d-restricted natural killer T (NKT) cells are innate lymphocytes that play a
regulatory role during an immune response. The identification of
-galactosylceramide ( -GalCer), a marine sponge-derived glycosphingolipid, ...
Cited by 46 - Related articles - BL Direct - All 5 versions

Natural killer T cells as targets for therapeutic intervention in autoimmune diseases


MT Wilson, LV Kaer - Frontiers in Medicinal Chemistry-Online, 2005 - ingentaconnect.com
Department of Microbiology and Immunology, Vanderbilt University School of
Medicine, Rudolph Light Hall, Room 811, Nashville, Tennessee 37232-0295, USA
Abstract: Natural killer T (NKT) cells are a subset of lymphocytes that ...
Cited by 35 - Related articles - BL Direct - All 4 versions

The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes …


SL Cardell - Clinical and Experimental Immunology, 2006 - pubmedcentral.nih.gov
Manipulation of the immune response to specifically prevent autoaggression
requires an understanding of the complex interactions that occur during the
pathogenesis of autoimmunity. Much attention has been paid to conventional ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+ CD25+ …

- jimmunol.org
D Ly, QS Mi, S Hussain, TL Delovitch - The Journal of Immunology, 2006 - Am Assoc Immnol
Invariant NK T (iNKT) cells regulate immune responses, express NK cell markers
and an invariant TCR, and recognize lipid Ags in a CD1d-restricted manner.
Previously, we reported that activation of iNKT cells by ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell …

- jimmunol.org
C Forestier, T Takaki, A Molano, JS Im, I … - The Journal of Immunology, 2007 - Am Assoc Immnol
Activation of CD1d-restricted invariant NKT (iNKT) cells by -galactosylceramide
( GalCer) significantly suppresses development of diabetes in NOD mice. The
mechanisms of this protective effect are complex, involving both Th1 and ...
Cited by 18 - Related articles - BL Direct - All 5 versions

Transforming growth factor-β and natural killer T-cells are involved in the protective effect of …

- shouxi.net
MA Alyanakian, F Grela, A Aumeunier, C … - Diabetes, 2006 - Am Diabetes Assoc
The onset of type 1 diabetes in NOD mice is delayed by oral administration of a
bacterial extract (OM-85) and can be completely prevented by its intraperitoneal
administration. Optimal prevention is observed when starting treatment at 3 ...
Cited by 16 - Related articles - BL Direct - All 6 versions

Regulation of type 1 diabetes by NKT cells


J Novak, T Griseri, L Beaudoin, A Lehuen - International Reviews of Immunology, 2007 - informahealthcare.com
Type 1 diabetes is an autoimmune disease due to the destruction of
insulin-producing pancreatic β cells. Natural Killer T (NKT) cells are a T-cell
subset that links the innate and adaptive immune systems. NKT cells play a ...
Cited by 11 - Related articles - All 4 versions

Efficient activation of V {alpha} 14 invariant NKT cells by foreign lipid antigen is associated …

- jimmunol.org
L Cheng, A Ueno, S Cho, JS Im, S Golby, S … - The Journal of Immunology, 2007 - Am Assoc Immnol
A burst release of cytokines by V 14 invariant NKT (iNKT) cells upon their TCR
engagement critically regulates innate and adaptive immune responses. However,
it remains unclear in vivo why iNKT cells respond efficiently to microbial ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes …

- jimmunol.org
S Hussain, TL Delovitch - The Journal of Immunology, 2007 - Am Assoc Immnol
Although B cells play a pathogenic role in the initiation of type 1 diabetes
(T1D) in NOD mice, it is not known whether activated B cells can maintain
tolerance and transfer protection from T1D. In this study, we demonstrate ...
Cited by 8 - Related articles - All 4 versions


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