- ►nih.gov KI Rother, DM Harlan - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Worldwide, more than 750 individuals with type 1 diabetes mellitus (T1DM) have
received allogeneic islet transplants since 1974, in an effort to cure their
chronic condition. Though this is still a small number (especially when ... Cited by 103 - Related articles - BL Direct - All 11 versions
Y Lai, D Schneider, A Kidszun, I Hauck- … - Transplantation, 2005 - journals.lww.com Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ... Cited by 47 - Related articles - All 4 versions
SM Clee, BS Yandell, KM Schueler, ME … - Nature - stat.wisc.edu We previously mapped the type 2 diabetes mellitus-2 locus (T2dm2), which affects
fasting insulin levels, to distal chromosome 19 in a leptin-deficient obese F2
intercross derived from C57BL/6 (B6) and BTBR T+ tf/J (BTBR) mice1. ... Cited by 46 - Related articles - View as HTML - BL Direct - All 12 versions
- ►diabetesjournals.org D Nyqvist, M Köhler, H Wahlstedt, PO … - Diabetes, 2005 - Am Diabetes Assoc Pancreatic islet transplantation has emerged as a therapy for type 1 diabetes
and is today performed using both freshly isolated and cultured islets. Islet
blood vessels are disrupted during islet isolation; therefore, proper ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org N Zhang, D Su, S Qu, T Tse, R Bottino, AN … - Diabetes, 2006 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large
quantities of islets, but only a fraction of transplanted islets can survive and
become engrafted, and yet the underlying mechanism remains unclear. In this ... Cited by 41 - Related articles - BL Direct - All 7 versions
- ►shouxi.net M Brissova, A Shostak, M Shiota, PO Wiebe, … - Diabetes, 2006 - Am Diabetes Assoc To investigate molecular mechanisms controlling islet vascularization and
revascularization after transplantation, we examined pancreatic expression of
three families of angiogenic factors and their receptors in differentiating ... Cited by 40 - Related articles - BL Direct - All 6 versions
- ►aspetjournals.org AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET Islet transplantation may be used to treat type I diabetes. Despite tremendous
progress in islet isolation, culture, and preservation, the clinical use of this
modality of treatment is limited due to post-transplantation challenges to ... Cited by 32 - Related articles - BL Direct - All 13 versions
- ►psu.edu [PDF] CS Nunemaker, M Zhang, DH Wasserman, OP … - Diabetes, 2005 - Am Diabetes Assoc Pulsatile insulin secretion in vivo is believed to be derived, in part, from the
intrinsic glucose-dependent intracellular calcium concentration ([Ca 2+ ] i )
pulsatility of individual islets. In isolation, islets display fast, slow, ... Cited by 24 - Related articles - BL Direct - All 10 versions
A King, J Lock, G Xu, S Bonner-Weir, GC Weir - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Although islet transplantation in diabetes holds great
promise, two or three donor pan- creases are usually required to achieve
normoglycaemia in human or rodent recipients. We investigated whether there ... Cited by 23 - Related articles - BL Direct - All 4 versions
