- ►nih.gov JM Huss, DP Kelly - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig All cellular processes are driven by ATP-dependent pathways. The heart has
perpetually high energy demands related to the maintenance of specialized
cellular processes, including ion transport, sarcomeric function, and ... Cited by 136 - Related articles - All 9 versions
S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that
globally the number of adults affected with diabetes will increase from 135
million in 1995 to 300 million by 2025. 1 Patients with diabetes mellitus ... Cited by 135 - Related articles - All 5 versions
D An, B Rodrigues - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure
usually develops in the presence of hypertension or ischemic heart disease.
However, a predisposition to heart failure might also reflect the effects ... Cited by 65 - Related articles - BL Direct - All 5 versions
X Shen, S Zheng, NS Metreveli, PN Epstein - Diabetes, 2006 - Am Diabetes Assoc We previously reported damage and elevated biogenesis in cardiac mitochondria of
a type 1 diabetic mouse model and proposed that mitochondria are one of the
major targets of oxidative stress. In this study, we targeted ... Cited by 54 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org S Boudina, S Sena, H Theobald, X Sheng, JJ … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—db/db hearts exhibited reduced cardiac function and increased MVo 2 .
Mitochondrial reactive oxygen species (ROS) generation and lipid and protein
peroxidation products were increased. Mitochondrial proliferation was ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►physiology.org S Boudina, ED Abel - Physiology, 2006 - Am Physiological Soc Diabetes is a worldwide epidemic (112). Cardiovascular disease remains the major
cause of morbidity and mortality in people with diabetes. Epidemiological
studies suggest that the prevalence of heart failure exceeds that which can ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org W Hsueh, ED Abel, JL Breslow, N Maeda, RC … - Circulation research, 2007 - Am Heart Assoc From the Division of Endocrinology, Diabetes, and Hypertension (WH), and
Department of Medicine, Division of Cardiology (RCD), The David Geffen School of
Medicine, University of California, Los Angeles; Division of Endocrinology, ... Cited by 37 - Related articles - All 6 versions
- ►ahajournals.org J Yang, N Sambandam, X Han, RW Gross, M … - Circulation research, 2007 - Am Heart Assoc Obesity-related diabetes mellitus leads to increased myocardial uptake of fatty
acids (FAs), resulting in a form of cardiac dysfunction referred to as lipotoxic
cardiomyopathy. We have shown previously that chronic activation of the FA- ... Cited by 38 - Related articles - All 6 versions
- ►amjpathol.org Y Song, J Wang, Y Li, Y Du, GE Arteel, JT … - American Journal of Pathology, 2005 - ASIP Oxidative stress is involved in the pathogenesis of diabetes and its
cardiovascular complications. Metallothionein (MT), a stress-response protein,
is significantly increased in the liver and kidney of diabetic animals. We ... Cited by 35 - Related articles - All 11 versions
- ►apps.org.au LC Hool - Clinical and Experimental Pharmacology and …, 2006 - pt.wkhealth.com Presented at the AuPS (AHMRC) Symposium Cardiac Hypertrophy and Failure:
Cellular and Signalling Defects, November 2004. The papers in these proceedings
were peer reviewed under the supervision of the AuPS Editor. The papers are ... Cited by 34 - Related articles - BL Direct - All 13 versions
