DT Odom, RD Dowell, ES Jacobsen, W Gordon, TW … - Nature genetics, 2007 - nature.com We demonstrate that the binding sites for highly conserved transcription factors vary extensively
between human and mouse. We mapped the binding of four tissue-specific transcription factors
(FOXA2, HNF1A, HNF4A and HNF6) to 4,000 orthologous gene pairs in hepatocytes ... Cited by 109 - Related articles - BL Direct - All 6 versions
M Vaxillaire, P Froguel - Endocrinology and metabolism clinics of North America, 2006 - Elsevier Type 2 diabetes mellitus (T2D) is a heterogeneous metabolic disease occurring with concomitant
or interdependent defects of insulin secretion and action [1] and [2]. It generally is accepted that
T2D results from a complex interplay of genetic and environmental factors influencing ... Cited by 30 - Related articles - All 4 versions
- ►gemstudy.ca [PDF] Y Yu, DF Wyszynski, DM Waterworth, SD Wilton, … - Science's …, 2005 - stke.sciencemag.org Abstract: We conducted a genome-wide scan using variance components linkage analysis to
localize quantitative-trait loci (QTLs) influencing triglyceride (TG), high density lipoprotein-cholesterol
(HDL-C), low density lipoprotein-cholesterol, and total cholesterol (TC) levels in 3,071 ... Cited by 23 - Related articles - BL Direct - All 7 versions
MT Tusié Luna - Archives of Medical Research, 2005 - Elsevier Type 2 diabetes (T2DM) comprises a group of entities with different genetic causes. In most
patients, T2DM results from alterations of various genes, each having a partial and additive
effect. The inheritance pattern is thus complex, and environmental factors play an ... Cited by 18 - Related articles - All 2 versions
- ►nih.gov M Borowiec, R Thompson, C Powers, R Xu, T Dickey, A … - Diabetologia, 2007 - Springer Page 1. RESEARCH LETTER Mutations in the SLC30A8 gene are not a major cause
of MODYor other forms of early-onset, autosomal dominant type 2 diabetes M. Borowiec
& R. Thompson & C. Powers & R. Xu & T. Dickey & A. Doria ... Cited by 6 - Related articles - BL Direct - All 4 versions
A Domínguez-López, Á Miliar-García, YX Segura- … - JOP. J Pancreas (Online …, 2005 - joplink.net Context Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes mellitus
characterized by autosomal dominant inheritance, early age of onset and a primary insulin secretion
defect. Certain MODY gene sequence variants may be involved in polygenic forms of type ... Cited by 5 - Related articles - Cached - All 3 versions
- ►endojournals.org M Vaxillaire, P Froguel - Endocrine Reviews, 2008 - Endocrine Soc Most valuable breakthroughs in the genetics of type 2 diabetes for the past two decades have
arisen from candidate gene studies and familial linkage analysis of maturity-onset diabetes of
the young (MODY), an autosomal dominant form of diabetes typically occurring before 25 ... Cited by 6 - Related articles - BL Direct - All 6 versions
… , T Hiekkalinna, K Schwander, S Kardia, … - European journal of …, 2009 - pubmedcentral.nih.gov Stature (adult body height), and body mass index (BMI) have a strong genetic component explaining
observed variation in human populations, however, identifying those genetic components has
been extremely challenging. It seems obvious that sample size is a critical determinant for ... Cited by 6 - Related articles - All 5 versions
S Chen, H Saiyin, X Zeng, J Xi, X Liu, X Li, L … - Cytogenet Genome …, 2006 - content.karger.com We have identified and isolated a novel human gene, HMBOX1 (homeobox containing 1) from
a pancreatic cDNA library. Human HMBOX1 is widely expressed in 18 tissues, and it is highly
expressed in pancreas. According to the genome database, HMBOX1 is located at the ... Cited by 4 - Related articles - BL Direct - All 5 versions
JS Dunn, WM Mlynarski, MG Pezzolesi, M … - Annals of Human …, 2006 - interscience.wiley.com The product of the PPP1R3B gene (G L ) is the regulatory subunit of PP1 - a serine/threonine
phosphatase involved in the modulation of glycogen synthesis in the liver and skeletal
muscle. The PPP1R3B gene is located on chromosome 8p23 in a region that has been ... Cited by 2 - Related articles - BL Direct - All 3 versions
