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Scholar Results 1 - 10 of about 65 citing Oberkofler: Complex haplotypes of the PGC-1α gene are associated with carbohydrate metabolism.... (0.10 sec) 

PGC-1 coactivators: inducible regulators of energy metabolism in health and …

- nih.gov
BN Finck, DP Kelly - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
Members of the nuclear receptor (NR) superfamily relay physiologic and nutritional cues to critical
gene regulatory responses. The molecular links between external stimuli, cellular signaling
events, and NR-mediated transcriptional control are currently being unraveled. New ...
Cited by 226 - Related articles - BL Direct - All 9 versions

PGC-1α deficiency causes multi-system energy metabolic derangements: muscle …


TC Leone, JJ Lehman, BN Finck, PJ Schaeffer, AR … - biology.plosjournals.org
The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a common
ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. They have
the same chromosome number and genome sizes, and they occupy the same ecological ...
Cited by 180 - Related articles - Cached - All 12 versions

Variants of ENPP1 are associated with childhood and adult obesity and increase …


D Meyre, N Bouatia-Naji, A Tounian, C Samson, … - Nature …, 2005 - pubmedcentral.nih.gov
We identified a childhood obesity locus on chromosome 6q16.3-q24.2 1 that includes 2.4 Mb
common to eight genome scans for Type 2 diabetes (T2D) or obesity 1 - 8 . Analysis of the ENPP1
(PC-1) gene, a candidate for insulin resistance 9 , 10 in 6,147 subjects revealed ...
Cited by 161 - Related articles - BL Direct - All 10 versions

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a …

- nthu.edu.tw [PDF] 
S Cauchi, Y El Achhab, H Choquet, C Dina, F … - Journal of Molecular …, 2007 - Springer
Page 1. RAPID COMMUNICATION TCF7L2 is reproducibly associated with type 2
diabetes in various ethnic groups: a global meta-analysis Stéphane Cauchi & Younes
El Achhab & Hélène Choquet & Christian Dina & Franz Krempler & ...
Cited by 99 - Related articles - BL Direct - All 4 versions

Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats

- nutrition.org
WJ Fu, TE Haynes, R Kohli, J Hu, W Shi, TE … - Journal of …, 2005 - Am Soc Nutrition
This study was conducted to test the hypothesis that dietary supplementation of arginine, the
physiologic precursor of nitric oxide (NO), reduces fat mass in the Zucker diabetic fatty (ZDF)
rat, a genetically obese animal model of type-II diabetes mellitus. Male ZDF rats, 9 wk old, ...
Cited by 74 - Related articles - All 5 versions

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-{gamma}( …

- endojournals.org
E Burgermeister, A Schnoebelen, A Flament, J … - Molecular …, 2006 - Endocrine Soc
Partial agonists of peroxisome proliferator-activated receptor- (PPAR ), also termed selective
PPAR modulators, are expected to uncouple insulin sensitization from triglyceride (TG) storage
in patients with type 2 diabetes mellitus. These agents shall thus avoid adverse effects, ...
Cited by 56 - Related articles - BL Direct - All 4 versions

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis …


P Flachs, O Horakova, P Brauner, M Rossmeisl, P … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 2365–2375 DOI 10.1007/s00125-005-1944-7 ARTICLE P. Flachs .
O. Horakova . P. Brauner . M. Rossmeisl . P. Pecina . N. Franssen-van Hal . J. Ruzickova . J.
Sponarova . Z. Drahota . C. Vlcek . J. Keijer . J. Houstek . J. Kopecky ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Peroxisome proliferator-activated receptor {gamma} coactivator-1 (PGC-1) …

- ahajournals.org
BN Finck, DP Kelly - Circulation, 2007 - Am Heart Assoc
The constant workload of the heart requires a high-capacity mitochondrial system to match ATP
production with functional demands. In the adult mammalian heart, ATP synthesis occurs primarily
through complete oxidation of fatty acids and glucose in the mitochondrion. Mitochondrial ...
Cited by 41 - Related articles - All 6 versions

Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and …


I Barroso, J Luan, MS Sandhu, PW Franks, V Crowley, … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis: Peroxisome proliferator-ac- tivated receptor-γ co-activator-1α
(PPARGC1A) is a transcriptional co-activator with a central role in energy expenditure and glucose
metabolism. Several studies have suggested that the common PPARGC1A polymor- ...
Cited by 37 - Related articles - BL Direct - All 4 versions

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective …

- diabetesjournals.org
M Vaxillaire, J Veslot, C Dina, C Proença, S Cauchi, G … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The GCK (Glucokinase) −30A allele was associated with increased type 2 diabetes
risk at the end of the follow-up study (adjusted OR 1.34 [95% CI 1.07–1.69]) under an additive
model, as supported in independent French diabetic case subjects (OR 1.22, P = 0.007), ...
Cited by 34 - Related articles - BL Direct - All 4 versions


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