- ►diabetesjournals.org S Fatrai, L Elghazi, N Balcazar, C Cras- … - Diabetes, 2006 - Am Diabetes Assoc Proliferation is the major component for maintenance of β-cell mass in adult
animals. Activation of phosphoinositide 3-kinase/Akt-kinase pathway is a
critical regulator of β-cell mass. Pancreatic β-cell overexpression of ... Cited by 42 - Related articles - BL Direct - All 5 versions
- ►jbc.org BS Finlin, AL Mosley, SM Crump, RN Correll, … - Journal of Biological Chemistry, 2005 - ASBMB Voltage-dependent calcium (Ca 2+ ) channels are involved in many specialized
cellular functions and are controlled by a diversity of intracellular signals.
Recently, members of the RGK family of small GTPases (Rem, Rem2, Rad, ... Cited by 38 - Related articles - BL Direct - All 5 versions
M Ohsugi, C Cras-Meneur, Y Zhou, E Bernal- … - Journal of Biological Chemistry, 2005 - ASBMB Running Title: Multiple roles of insulin signaling in islet cells ... Reduced
Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals
Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, ... Cited by 37 - Related articles - All 5 versions
- ►shouxi.net SC Martinez, C Cras-Méneur, E Bernal- … - Diabetes, 2006 - Am Diabetes Assoc Glucose controls islet β-cell mass and function at least in part through the
phosphatidylinositol 3-kinase (PI3K)/Akt pathway downstream of insulin
signaling. The Foxo proteins, transcription factors known in other tissues ... Cited by 32 - Related articles - BL Direct - All 6 versions
- ►endocrinology-journals.org M Schutt, J Zhou, M Meier, HH Klein - Journal of Endocrinology, 2004 - Soc Endocrinology The mechanism by which chronic treatment with HIV (human immunodeficiency
virus)-1 protease inhibitors leads to a deterioration of glucose metabolism
appears to involve insulin resistance, and may also involve impaired ... Cited by 24 - Related articles - All 4 versions
- ►jbc.org NL Vanderford, SS Andrali, S Ozcan - Journal of Biological Chemistry, 2007 - ASBMB MafA is a basic leucine zipper transcription factor that regulates gene
expression in both the neuroretina and pancreas. Within the pancreas, MafA is
exclusively expressed in the beta cells and is involved in insulin gene ... Cited by 15 - Related articles - All 8 versions
E Roche, J Jones, MI Arribas, T Leon-Quinto, … - Bioorganic & medicinal chemistry, 2006 - Elsevier The use of small specific molecules has been instrumental in the modulation of
stem cell proliferation and differentiation to obtain insulin-containing cells.
Examples include nutrients (glucose, nicotinamide and retinoic acid), acids ... Cited by 11 - Related articles - All 6 versions
- ►endocrinology-journals.org IC Greenman, E Gomez, CEJ Moore, TP … - Journal of Endocrinology, 2007 - Soc Endocrinology In pancreatic ß-cells, following an acute (within 1 h) increase in glucose
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proteins. The change in the expression of many of these proteins is ... Cited by 12 - Related articles - BL Direct - All 8 versions
KJ Chang-Chen, R Mullur, E Bernal-Mizrachi - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer Abstract Type 2 diabetes mellitus is a complex disease characterized by b-cell
failure in the setting of insulin resistance. In early stages of the disease,
pancreatic b-cells adapt to insulin resistance by increasing mass and ... Cited by 11 - Related articles - All 2 versions
- ►rupress.org L Seu, GS Pitt - Journal of General Physiology, 2006 - jgp.rupress.org Although inhibition of voltage-gated calcium channels by RGK GTPases (RGKs)
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cells, their exact mechanism of inhibition remains controversial. This has ... Cited by 10 - Related articles - BL Direct - All 5 versions
