AL Gloyn, J Siddiqui, S Ellard - Human mutation, 2006 - interscience.wiley.com The beta-cell ATP-sensitive potassium channel is a key component of
stimulus-secretion coupling in the pancreatic beta-cell. The channel couples
metabolism to membrane electrical events, bringing about insulin secretion. ... Cited by 32 - Related articles - BL Direct - All 3 versions
I Giurgea, C Bellanné-Chantelot, M Ribeiro, L … - Horm Res, 2006 - content.karger.com Congenital hyperinsulinism (CHI), characterized by profound hypoglycaemia
related to inappropriate insulin secretion, may be associated histologically
with either diffuse insulin hypersecretion or focal adenomatous ... Cited by 21 - Related articles - BL Direct - All 5 versions
- ►nih.gov T Flatt, KJ Min, C D'Alterio, E Villa-Cuesta, … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Ablation of germ-line precursor cells in Caenorhabditis elegans extends lifespan
by activating DAF-16, a forkhead transcription factor (FOXO) repressed by
insulin/insulin-like growth factor (IGF) signaling (IIS). Signals from the ... Cited by 20 - Related articles - BL Direct - All 10 versions
P Lonlay, I Giurgea, C Sempoux, G Touati, F … - Journal of inherited metabolic disease, 2005 - Springer Page 1. Dominantly inherited hyperinsulinaemic hypoglycaemia P. de Lonlay 1* ,
I. Giurgea 1 , C. Sempoux 4 , G. Touati 1 , F. Jaubert 1 , ... Cited by 16 - Related articles - All 5 versions
K Hussain - Horm Res, 2008 - content.karger.com Hyperinsulinaemic hypoglycaemia is a cause of persistent hypoglycaemia in the
neonatal and infancy periods. Prompt recognition and management of patients with
hyperinsulinaemic hypoglycaemia are essential, if brain damage and ... Cited by 12 - Related articles - BL Direct - All 5 versions
BH Dekelbab, MA Sperling - Acta Paediatrica, 2006 - sepeap.es Abstract Hyperinsulinemia-induced hypoglycemia is the most common cause of
persistent hypoglycemia in adults, children, and infants. Our understanding of
the disorders responsible for this type of hypoglycemia has been increasing ... Cited by 10 - Related articles - View as HTML - BL Direct - All 7 versions
KJ Lindley, MJ Dunne - Early human development, 2005 - Elsevier Congenital hyperinsulinism (CHI) is a genetically and phenotypically diverse
syndrome. Key management issues involve early diagnosis by ensuring that
appropriate samples are taken at the point of hypoglycaemia, prevention of ... Cited by 8 - Related articles - All 7 versions
V Valayannopoulos, S Romano, K Mention, A … - European Journal of Pediatrics, 2008 - Springer Page 1. REVIEW What's new in metabolic and genetic hypoglycaemias: diagnosis
and management Vassili Valayannopoulos & Stéphane Romano ... Cited by 6 - Related articles - BL Direct - All 2 versions
K Højlund, JFP Wojtaszewski, J Birk, BF … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Recently we reported the coexistence of postprandial
hypoglycaemia and moderate insulin resis- tance in heterozygous carriers of the
Arg1174Gln mutation in the insulin receptor gene (INSR). Controlled studies ... Cited by 5 - Related articles - BL Direct - All 3 versions
- ►eje.org HBT Christesen, ND Tribble, A Molven, J … - European Journal of Endocrinology, 2008 - eje.org Results: In five patients, four heterozygous GCK mutations (S64Y, T65I, W99R and
A456V) were identified, out of which S64Y was novel. Two of the mutations arose
de novo, three were dominantly inherited. All the five patients were ... Cited by 7 - Related articles - All 7 versions
