TP Di Lorenzo, M Peakman, BO Roep - Clinical and Experimental Immunology, 2007 - pubmedcentral.nih.gov T cell epitopes represent the molecular code words through which the adaptive
immune system communicates. In the context of a T cell-mediated autoimmune
disease such as type 1 diabetes, CD4 and CD8 T cell recognition of islet ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►shouxi.net Y Hassainya, F Garcia-Pons, R Kratzer, V … - Diabetes, 2005 - Am Diabetes Assoc Type 1 diabetes is thought to result from the destruction of β-cells by
autoantigen-specific T-cells. Observations in the NOD mouse model suggest that
CD8 + cytotoxic T-cells play an essential role in both the initial ... Cited by 43 - Related articles - All 6 versions
- ►pnas.org A Doi, T Shono, M Nishi, H Furuta, H Sasaki, … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences Ghrelin is a newly discovered peptide and an endogenous ligand for growth
hormone (GH) secretagogue (GHS) receptor. It has been shown to possess various
central and peripheral effects, including GH secretion, food intake, and ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org B Faideau, C Lotton, B Lucas, I Tardivel, JF … - The Journal of Immunology, 2006 - Am Assoc Immnol Proinsulin is a key Ag in type 1 diabetes, but the mechanisms regulating
proinsulin immune tolerance are unknown. We have shown that preproinsulin-2
gene-deficient mice (proins-2 –/– ) are intolerant to proinsulin-2. In ... Cited by 14 - Related articles - BL Direct - All 5 versions
A Kubosaki, S Nakamura, AL Notkins - Diabetes, 2005 - Am Diabetes Assoc IA-2 and IA-2β are members of the transmembrane protein tyrosine phosphatase
family located in dense core vesicles of neuroendocrine cells, including the
β-cells of pancreatic islets. In the present study, by mating C57BL/6Nci ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►endojournals.org A Kubosaki, S Nakamura, A Clark, JF Morris, … - Endocrinology, 2006 - Endocrine Soc Female infertility is a worldwide problem affecting 10–15% of the population.
The cause of the infertility in many cases is not known. In the present report,
we demonstrate that alterations in two transmembrane structural proteins, ... Cited by 10 - Related articles - BL Direct - All 5 versions
C Wasmeier, PV Burgos, T Trudeau, HW … - Traffic, 2005 - assets0.pubget.com Integral membrane proteins of neuroendocine dense- core vesicles (DCV) appear to
undergo multiple rounds of exocytosis; however, their trafficking and site of
incorporation into nascent DCVs is unclear. Previous studies with phogrin ... Cited by 10 - Related articles - View as HTML - All 5 versions
WJ Hendriks, A Elson, S Harroch, AW Stoker - FEBS journal, 2008 - assets0.pubget.com Research on how oncoviruses transform mammalian cells has led to the firm
establishment of the tyrosine- specific phosphorylation of cellular proteins as
a key signalling mechanism to evoke essential cell decisions, for example ... Cited by 10 - Related articles - View as HTML - BL Direct - All 8 versions
- ►nih.gov [PDF] D Homann, GS Eisenbarth - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Autoimmune diseases such as the diabetes that develops in NOD mice depend on
immunologic recognition of specific autoantigens, but recognition can result in
a pathogenic or protective T cell response. A study by Du et al. in this ... Cited by 9 - Related articles - BL Direct - All 10 versions