- ►ahajournals.org A Goldin, JA Beckman, AM Schmidt, MA … - Circulation, 2006 - Am Heart Assoc Advanced glycation end products (AGEs) are proteins or lipids that become
glycated after exposure to sugars. AGEs are prevalent in the diabetic
vasculature and contribute to the development of atherosclerosis. The ... Cited by 193 - Related articles - All 7 versions
I Dalle-Donne, G Aldini, M Carini, R Colombo, … - Journal of Cellular and Molecular Medicine, 2006 - interscience.wiley.com Carbonylation of proteins is an irreversible oxidative damage, often leading to
a loss of protein function, which is considered a widespread indicator of severe
oxidative damage and disease-derived protein dysfunction. Whereas ... Cited by 87 - Related articles - BL Direct - All 3 versions
GL Bakris, AJ Bank, DA Kass, JM Neutel, RA … - American Journal of Hypertension, 2004 - Elsevier Mechanisms by which AGE affect the cardiovascular system include AGE
cross-linking of long-lived proteins such as collagen and elastin and altered
cellular responses. Alagebrium (3-phenacyl-4,5-dimethylthiazolium chloride, ... Cited by 81 - Related articles - All 8 versions
- ►ahajournals.org AC Calkin, JM Forbes, CM Smith, M Lassila, … - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc Methods and Results— Control and diabetic apolipoprotein E–deficient mice
received rosiglitazone or placebo. Diabetic mice demonstrated a 3-fold increase
in plaque area, which was attenuated by rosiglitazone. There was no ... Cited by 79 - Related articles - All 9 versions
ME Cooper - American journal of hypertension, 2004 - Elsevier Although the features of diabetic cardiomyopathy, atherosclerosis, and
nephropathy have been clinically characterized, the pathogenesis and the
mechanisms underlying the abnormalities in the diabetic heart and kidney ... Cited by 59 - Related articles - All 10 versions
E Schleicher, U Friess - Kidney International, 2007 - nature.com Numerous reports on the molecular mechanism of atherogenesis indicate an
increase in oxidative stress, formation of advanced glycoxidation end products
(AGEs), chronic inflammation, and activated cellular response particularly ... Cited by 45 - Related articles - BL Direct - All 3 versions
MC Thomas, JW Baynes, SR Thorpe, ME … - Current Drug Targets, 2005 - ingentaconnect.com Abstract: Prolonged hyperglycemia, dyslipidemia and oxidative stress in diabetes
result in the production and accumulation of AGEs. It is now clear that AGEs
contribute to the development and progression of cardiovascular disease in ... Cited by 42 - Related articles - All 2 versions
- ►diabetesjournals.org … JG Regensteiner, H Vlassara, JEB Reusch - Diabetes Care, 2006 - Am Diabetes Assoc The morbidity caused by diabetes has traditionally been classified into macro-
and microvascular complications. Although macrovascular complications have
received greater attention, microvascular complications are unique to ... Cited by 41 - Related articles - All 6 versions
- ►endojournals.org SY Goh, ME Cooper - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Evidence Synthesis: In this review we report on how these AGEs may exert
deleterious effects in diabetes, as well as address current strategies to
interrupt the formation or action of AGEs. First, AGEs act directly to ... Cited by 43 - Related articles - BL Direct - All 4 versions
G Aldini, I Dalle-Donne, RM Facino, A Milzani, … - Medicinal Research Reviews, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 41 - Related articles - BL Direct - All 3 versions
