DA Antonetti, AJ Barber, SK Bronson, WM Freeman, … - Diabetes, 2006 - Am Diabetes Assoc Diabetic retinopathy remains a frightening prospect to patients and frustrates physicians. Destruction
of damaged retina by photocoagulation remains the primary treatment nearly 50 years after its
introduction. The diabetes pandemic requires new approaches to understand the ... Cited by 73 - Related articles - BL Direct - All 9 versions
K Maiese, SD Morhan, ZZ Chong - Current neurovascular …, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) affects approximately 170 million individuals worldwide and is expected
to alter the lives of at least 366 million individuals within a future span of 25 years. Of even greater
concern is the premise that these projections are underestimated since they assume ... Cited by 46 - Related articles - BL Direct - All 6 versions
PH Groop, C Forsblom, MC Thomas - Nature clinical practice. …, 2005 - ncbi.nlm.nih.gov Resistance to the actions of insulin is strongly associated with the microvascular complications
of diabetes. To the extent that insulin resistance leads to hyperglycemia, dyslipidemia and
hypertension, this association is not surprising. It is now clear that insulin also has direct ... Cited by 36 - Related articles - BL Direct - All 5 versions
CEN Reiter, X Wu, L Sandirasegarane, M Nakamura, … - Diabetes, 2006 - Am Diabetes Assoc Diabetic retinopathy is characterized by early onset of neuronal cell death. We previously showed
that insulin mediates a prosurvival pathway in retinal neurons and that normal retina expresses
a highly active basal insulin receptor/Akt signaling pathway that is stable throughout ... Cited by 33 - Related articles - BL Direct - All 5 versions
TJ Huang, A Verkhratsky, P Fernyhough - Molecular and Cellular Neuroscience, 2005 - Elsevier We tested the hypothesis that neurotrophic factors control neuronal metabolism by directly regulating
mitochondrial function in the absence of effects on survival. Real-time whole cell fluorescence
video microscopy was utilized to analyze mitochondrial inner membrane potential (Δψ m ... Cited by 32 - Related articles - All 6 versions
- ►ruhr-uni-bochum.de [PDF] BM Lobnig, O Kromeke, C Optenhostert-Porst, OT … - Diabetic Medicine, 2006 - pt.wkhealth.com Methods: In a case-control design, 13 Type 1 diabetic patients with at least 10 years' duration
of disease, but free from clinical signs of macrovascular disease, were compared with age- and
gender-matched control subjects. Hippocampal volume and measures of global cerebral ... Cited by 32 - Related articles - BL Direct - All 9 versions
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) is a significant healthcare concern worldwide that affects more than 165
million individuals leading to cardiovascular disease, nephropathy, retinopathy, and widespread
disease of both the peripheral and central nervous systems. The incidence of ... Cited by 27 - Related articles - BL Direct - All 6 versions
GM Leinninger, JL Edwards, MJ Lipshaw, EL … - Nature Clinical Practice …, 2006 - nature.com Eva L Feldman received her MD and Ph.D. in Neuroscience at the University of Michigan, Ann
Arbor, MI, USA and completed her residency in Neurology at the Johns Hopkins Hospital,
Baltimore, PA, USA. She returned to the University of Michigan, where she is the Russell ... Cited by 27 - Related articles - BL Direct - All 3 versions
C Toth, V Brussee, DW Zochodne - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: The support of distal regen- erating axons and epidermal nerve fibres
through growth factor delivery may depend on the site of delivery. While low-dose systemic insulin
provides trophic support for regenerating axons or axons from diabetic animals, its ... Cited by 25 - Related articles - BL Direct - All 3 versions
