- ►cell.com SHS Pearce, TR Merriman - Trends in molecular medicine, 2006 - Elsevier The past few years have seen the identification of PTPN22 and the confirmation
of CTLA-4 as common autoimmune disease genes. Together with MHC and INS, these
developments have increased the collection of confirmed susceptibility loci ... Cited by 46 - Related articles - All 5 versions
D Owerbach, EM McKay, ETH Yeh, KH … - Biochemical and Biophysical Research …, 2005 - Elsevier Four small ubiquitin-related modifier (SUMO) genes have been identified in
humans. However, little is known about the basic biology of SUMO-4. Here, we
report that SUMO-4 differs from SUMO-1, -2, and -3 in that the maturation ... Cited by 43 - Related articles - All 4 versions
- ►endojournals.org MJ Simmonds, JM Heward, J Carr-Smith, H … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Recently six DNA variants, two of which (M55V and 001Msp) are present
in nuclear factor- B inhibitors SUMO-4 and MAP3K7IP2 and four of which (fcrl3_3,
fcrl3_4, fcrl3_5, and fcrl3_6) modulate nuclear factor- B binding and ... Cited by 38 - Related articles - BL Direct - All 4 versions
M Li, D Guo, CM Isales, DL Eizirik, M … - Journal of Molecular Medicine, 2005 - Springer Page 1. J Mol Med (2005) 83: 504–513 DOI 10.1007/s00109-005-0645-5 REVIEW Manyu
Li . Dehuang Guo . Carlos M. Isales . Decio L. Eizirik . Mark Atkinson . ... Cited by 32 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org S Noso, H Ikegami, T Fujisawa, Y Kawabata, K … - Diabetes, 2005 - Am Diabetes Assoc Association studies are a potentially powerful approach to identifying
susceptibility variants for common multifactorial diseases such as type 1
diabetes, but the results are not always consistently reproducible. The ... Cited by 28 - Related articles - BL Direct - All 5 versions
R Kosoy, P Concannon - Genes and Immunity, 2005 - nature.com Several functional genetic variants that can potentially modulate the activity
of NF B have been recently described. As reduced NF B activity has been
implicated in risk for autoimmune diabetes in the NOD mouse, these variants ... Cited by 23 - Related articles - All 2 versions
- ►endojournals.org M Tsurumaru, E Kawasaki, H Ida, K Migita, A … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Recently, an association of a single nucleotide polymorphism, 163A>G
encoding M55V, in the gene SUMO4, which has been shown to be a negative feedback
regulator for nuclear factor B, has been reported in type 1 diabetes. Cited by 21 - Related articles - BL Direct - All 4 versions
C Wang, R Podolsky, J She - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2006 - interscience.wiley.com Abstract: Genomewide linkage analyses since the early 1990s suggested over 20
genomic intervals that may contain susceptibility genes for type 1 diabetes.
However, the identification of the specific genes in these intervals ... Cited by 18 - Related articles - BL Direct - All 4 versions
H Ikegami, T Fujisawa, Y Kawabata, S Noso, … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2006 - interscience.wiley.com Abstract: Transracial studies are a powerful tool for genetic association
studies of multifactorial diseases, such as type 1 diabetes. We therefore
studied the association of candidate genes, HLA, INS, CTLA4, PTPN22, and ... Cited by 15 - Related articles - BL Direct - All 4 versions
