GR Kazeem, M Farrall - Annals of Human Genetics, 2005 - interscience.wiley.com Genetic-association studies are widely expected to unravel the genetic basis of
complex diseases. The population-based case-control study, a commonly used
approach for association studies, is subject to the problem of population ... Cited by 53 - Related articles - All 3 versions
- ►pnas.org PY Woon, PJ Kaisaki, J Bragança, MT … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Many aspects of physiology and behavior follow a circadian rhythm. Brain and
muscle Arnt-like protein-1 (BMAL1) is a key component of the mammalian molecular
clock, which controls circadian oscillations. In the rat, the gene encoding ... Cited by 29 - Related articles - BL Direct - All 8 versions
NK Prasad, SJ Decker - Journal of Biological Chemistry, 2005 - ASBMB Phosphoinositide lipid second messengers are integral components of signaling
pathways mediated by insulin, growth factors, and integrins. SHIP2
dephosphorylates phosphatidylinositol 3,4,5-trisphosphate generated by the ... Cited by 23 - Related articles - All 5 versions
- ►shouxi.net K Fukui, T Wada, S Kagawa, K Nagira, M … - Diabetes, 2005 - Am Diabetes Assoc We investigated the role of hepatic SH2-containing inositol 5′-phosphatase 2
(SHIP2) in glucose metabolism in mice. Adenoviral vectors encoding wild-type
SHIP2 (WT-SHIP2) and a dominant-negative SHIP2 (ΔIP-SHIP2) were injected ... Cited by 24 - Related articles - All 5 versions
MV Astle, G Seaton, EM Davies, CG Fedele, P … - IUBMB life, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 16 - Related articles - BL Direct - All 5 versions
KJ Wallace, RH Wallis, SC Collins, K Argoud, … - Physiological Genomics, 2004 - Am Physiological Soc Genetic studies in human populations and rodent models have identified regions
of human chromosome 1q21–25 and rat chromosome 2 showing evidence of
significant and replicated linkage to diabetes-related phenotypes. To ... Cited by 14 - Related articles - All 8 versions
- ►endojournals.org S Kagawa, T Sasaoka, S Yaguchi, H Ishihara, … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc TYPE 2 (NONINSULIN DEPENDENT) diabetes mellitus is a disorder characterized by
insulin resistance in the target tissue of insulin with insufficient insulin
secretion in pancreatic ß-cells (1). The molecular mechanisms underlying ... Cited by 10 - Related articles - All 4 versions
- ►ahajournals.org R DeKroon, JB Robinette, AB Hjelmeland, E … - Circulation research, 2006 - Am Heart Assoc Endothelial cell dysfunction and apoptosis are critical in the pathogenesis of
atherosclerotic cardiovascular disease (CVD). Both endothelial cell apoptosis
and atherosclerosis are reduced by high-density lipoprotein (HDL). Low HDL ... Cited by 6 - Related articles - All 7 versions
- ►endojournals.org S Kagawa, Y Soeda, H Ishihara, T Oya, M … - Endocrinology, 2008 - Endocrine Soc SH2-containing inositol 5'-phosphatase 2 (SHIP2) is a 5'-lipid phosphatase
hydrolyzing the phosphatidylinositol (PI) 3-kinase product PI(3,4,5)P 3 to
PI(3,4)P 2 in the regulation of insulin signaling, and is shown to be ... Cited by 4 - Related articles - BL Direct - All 3 versions
D Gauguier - Diabetologia, 2006 - Springer The last decade has seen remarkable advances in mammalian genome annotations and
has delivered improved genetic resources and genotyping technologies that should
prove crucial for tackling the genetic determinants of type 1 and type 2 ... Cited by 3 - Related articles - BL Direct - All 2 versions
