- ►physoc.org FC Howarth, M Jacobson, M Shafiullah, E … - Experimental physiology, 2005 - Physiological Soc In vivo biotelemetry studies have demonstrated that short-term streptozotocin
(STZ)-induced diabetes is associated with a reduction in heart rate (HR) and
heart rate variability (HRV) and prolongation of QT and QRS intervals. This ... Cited by 32 - Related articles - BL Direct - All 14 versions
- ►physiology.org N Yaras, A Bilginoglu, G Vassort, B Turan - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc Stimulation of local renin-angiotensin system and increased levels of oxidants
characterize the diabetic heart. Downregulation of ANG II type 1 receptors (AT 1
) and enhancement in PKC activity in the heart point out the role of AT 1 ... Cited by 14 - Related articles - BL Direct - All 5 versions
S Ozdemir, M Ugur, H Gürdal, B Turan - Archives of Biochemistry and Biophysics, 2005 - Elsevier We investigated the effect of treatment with an angiotensin II receptor blocker,
candesartan-cilexetil, on the mechanical and electrophysiological properties of
cardiomyocytes isolated from streptozotocin-induced diabetic (STZ) rats. ... Cited by 13 - Related articles - All 3 versions
VP Singh, B Le, R Khode, KM Baker, R Kumar - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Many of the effects of angiotensin (Ang) II are mediated through
specific plasma membrane receptors. However, Ang II also elicits biological
effects from the interior of the cell (intracrine), some of which are not ... Cited by 9 - Related articles - All 3 versions
- ►physiology.org E de Cavanagh, L Ferder, JE Toblli, B … - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc To investigate whether ANG II type 1 (AT 1 ) receptor blockade could protect
kidney mitochondria in streptozotocin-induced Type 1 diabetes, we treated
8-wk-old male Sprague-Dawley rats with a single streptozotocin injection ... Cited by 8 - Related articles - BL Direct - All 4 versions
FC Howarth, R Al-Sharhan, A Al-Hammadi, … - Molecular and cellular biochemistry, 2007 - Springer Abstract In vivo biotelemetry studies have demon- strated that heart rate (HR)
is progressively and rap- idly reduced after administration of streptozotocin
(STZ) and that the reduction in HR can be partially normalized with insulin ... Cited by 4 - Related articles - BL Direct - All 6 versions
S Wenzel, G Soltanpour, KD Schlüter - Pflügers Archiv European Journal of Physiology, 2005 - Springer Abstract Besides the classical cardiovascular diseases, high levels of blood
glucose directly interfere with car- diomyocytes. The mechanisms responsible for
this have not yet been explored in detail. This study aims to determine if ... Cited by 4 - Related articles - BL Direct - All 3 versions
MR Dent, T Singal, PS Tappia, SK Gupta, NS … - Current Trends in Pharmacology, 2007 - books.google.com Involvement of Renin- Angiotensin System in the Pathogenesis of Cardiovascular
Disease Melissa R Dent, Tushi Singal, Paramjit S Tappia, Suresh K Gupta,
Naranjan S Dhalla* INTRODUCTION Cardiovascular disease remains the major ... Cited by 2 - Related articles
- ►physiology.org Y Shimoni, D Hunt, K Chen, T Emmett, G … - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc The autocrine modulation of cardiac K + currents was compared in ventricular and
atrial cells (V and A cells, respectively) from Type 1 diabetic rats. K +
currents were measured by using whole cell voltage clamp. ANG II was ... Cited by 2 - Related articles - All 3 versions
D Senador, K Kanakamedala, MC Irigoyen, M … - Experimental Physiology, 2009 - Physiological Soc The db/db mice serve as a good model for type 2 diabetes characterized by
hyperinsulinaemia and progressive hyperglycaemia. There are limited and
conflicting data on the cardiovascular changes in this model. The aim of ... Cited by 1 - Related articles - All 8 versions
