PE Cryer - Diabetes, 2005 - Am Diabetes Assoc Iatrogenic hypoglycemia is a problem for people with diabetes. It causes
recurrent morbidity, and sometimes death, as well as a vicious cycle of
recurrent hypoglycemia, precluding maintenance of euglycemia over a ... Cited by 72 - Related articles - BL Direct - All 7 versions
B Xue, BB Kahn - The Journal of physiology, 2006 - Physiological Soc The evolutionarily conserved serine/threonine kinase, AMP-activated protein
kinase (AMPK), functions as a cellular fuel gauge that regulates metabolic
pathways in glucose and fatty acid metabolism and protein synthesis. Recent ... Cited by 69 - Related articles - BL Direct - All 8 versions
- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
S Ramamurthy, GV Ronnett - The Journal of physiology, 2006 - Physiological Soc The 5′-adenosine monophosphate-activated protein kinase (AMPK) is a metabolic
and stress sensor that has been functionally conserved throughout eukaryotic
evolution. Activation of the AMPK system by various physiological or ... Cited by 41 - Related articles - BL Direct - All 9 versions
- ►ufsc.br [PDF] Q Gao, TL Horvath, 2007 - Annual Reviews Abstract Significant advancements have been made in the past century regarding
the neuronal control of feeding behavior and energy expenditure. The effects and
mechanisms of action of various peripheral metabolic signals on the brain ... Cited by 41 - Related articles - BL Direct - All 5 versions
SM Han, C Namkoong, PG Jang, IS Park, SW … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 2170–2178 DOI 10.1007/s00125-005-1913-1 ARTICLE
S.-M. Han . C. Namkoong . PG Jang . IS Park . SW Hong . H. Katakami . ... Cited by 30 - Related articles - BL Direct - All 3 versions
MS Kim, KU Lee - Journal of molecular medicine, 2005 - Springer Abstract Although obesity is an epidemic threat to general health worldwide, an
effective treatment has yetto befound. Insights into weight-regulatory pathways
will accelerate the identification of new molecular targets for ... Cited by 29 - Related articles - BL Direct - All 5 versions
DG Hardie - FEBS letters, 2008 - Elsevier Obesity, type 2 diabetes and the metabolic syndrome are disorders of energy
balance, which the AMP-activated protein kinase (AMPK) regulates both at the
cellular and whole body levels. AMPK switches cells from an anabolic state ... Cited by 30 - Related articles - All 11 versions
- ►nih.gov RJ McCrimmon, Z Song, H Cheng, EC McNay, … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Recurrent episodes of hypoglycemia impair sympathoadrenal counterregulatory
responses (CRRs) to a subsequent episode of hypoglycemia. For individuals with
type 1 diabetes, this markedly increases (by 25-fold) the risk of severe ... Cited by 29 - Related articles - BL Direct - All 11 versions
- ►diabetesjournals.org RJ McCrimmon, X Fan, H Cheng, E McNay, O … - Diabetes, 2006 - Am Diabetes Assoc Defective counterregulatory responses (CRRs) to hypoglycemia are associated with
a marked increase in the risk of severe hypoglycemia. The mechanisms leading to
the development of defective CRRs remain largely unknown, although they are ... Cited by 28 - Related articles - BL Direct - All 5 versions
