- ►bloodjournal.org [PDF] I Kim, OH Yilmaz, SJ Morrison - Blood, 2005 - Am Soc Hematology . Hematology; all rights reserved Copyright 2007 by The American Society of DC 20036. by the
American Society of Hematology, 1900 M St, NW, Suite 200, Washington Blood (print ISSN
0006-4971, online ISSN 1528-0020), is published semimonthly ... For personal use only. ... Cited by 40 - Related articles - BL Direct - All 9 versions
- ►hematologylibrary.org R Mallone, SA Kochik, H Reijonen, B Carson … - …, 2005 - bloodjournal.hematologylibrary.org One of the key determinants of differential outcomes for both autoimmune and normal T-cell responses
is the functional T-cell avidity. The overall T-cell avidity is determined by a number of
components, including the intrinsic TCR affinity for the peptide-MHC complex; the ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►pnas.org M Ráki, LE Fallang, M Brottveit, E … - Proceedings of the …, 2007 - National Acad Sciences Tetramers of MHC–peptide complexes are used for detection and characterization of
antigen-specific T cell responses, but they require knowledge about both antigenic peptide and
the MHC restriction element. The successful application of these reagents in human ... Cited by 17 - Related articles - BL Direct - All 9 versions
- ►oxfordjournals.org A Quinn, M McInerney, D Huffman, B … - International …, 2006 - Jpn Soc Immunol Non-obese diabetic (NOD) mice spontaneously develop autoimmune diabetes, and serve as
a model for type 1 diabetes (T1D) and natural autoimmunity. T cell responses to the pancreatic
islet antigen glutamic acid decarboxylase 65 (GAD65) can be detected in the spleens of ... Cited by 9 - Related articles - BL Direct - All 5 versions
T Brusko, M Atkinson - Cell biochemistry and biophysics, 2007 - Springer Abstract At the time of this writing, a major void exists; the lack of a method to prevent and/or
reverse type 1 diabetes in humans. We believe this void to a large extent is the result of our lack
in understanding the mechanisms of autoimmunity that underlie b cell destruction, a ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►nih.gov JA Gebe, KA Unrath, BB Yue, T Miyake, BA Falk, GT … - Journal of autoimmunity, 2008 - Elsevier A human T-cell receptor (TcR) derived from an autoreactive T-cell specific for GAD65, from a
subject at high risk for autoimmune diabetes, was introduced into HLA-DR4 transgenic mice.
The source of TcR was a CD4 + T H 1 + T-cell clone which responded to an ... Cited by 8 - Related articles - All 3 versions
- ►nih.gov JA Gebe, KA Unrath, BA Falk, K Ito, L Wen, TL Daniels, … - Clinical Immunology, 2006 - Elsevier We have identified for the first time an age-dependent spontaneous loss of tolerance to two
self-antigenic epitopes derived from putative diabetes-associated antigens glutamic acid decarboxylase
(GAD65) and glial fibrillary acidic protein (GFAP) in RIP-B7/DRB1*0404 HLA transgenic ... Cited by 6 - Related articles - All 4 versions
MDFS Barbosa, E Celis - Drug discovery today, 2007 - Elsevier Patients can mount sustained immune responses to protein therapeutics with the production
of neutralizing antibodies (NAbs) that can compromise efficacy or safety of these drugs. Dendritic
cells (DCs) are required for immunoglobulin (Ig) isotype switching and the production of ... Cited by 6 - Related articles - All 4 versions
- ►nih.gov EM Laughlin, JD Miller, E James, D Fillos, CC … - Infection and …, 2007 - Am Soc Microbiol Detection of antigen-specific CD4 + T cells is facilitated by the use of fluorescently labeled soluble
peptide-major histocompatibility complex (MHC) multimers which mirror the antigen specificity
of T-cell receptor recognition. We have used soluble peptide-MHC class II tetramers ... Cited by 4 - Related articles - BL Direct - All 9 versions
A Immonen, T Kinnunen, P Sirven, A … - Clinical and …, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 4 - Related articles - BL Direct - All 4 versions
