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Scholar Results 1 - 10 of about 19 citing Chilton: Flt3-ligand treatment prevents diabetes in NOD mice. (0.10 sec) 

The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen …

- pnas.org
P Schnorrer, G Behrens, NS Wilson, JL … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Mouse spleens contain three populations of conventional (CD11c high ) dendritic
cells (DCs) that play distinct functions. The CD8 + DC are unique in that they
can present exogenous antigens on their MHC class I molecules, a process ...
Cited by 92 - Related articles - BL Direct - All 11 versions

TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in …

- jimmunol.org
D Zipris, E Lien, A Nair, JX Xie, DL Greiner, … - The Journal of Immunology, 2007 - Am Assoc Immnol
Viral infections are associated epidemiologically with the expression of type 1
diabetes in humans, but the mechanisms underlying this putative association are
unknown. To investigate the role of viruses in diabetes, we used a model of ...
Cited by 28 - Related articles - BL Direct - All 7 versions

Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined …

- oxfordjournals.org
M O'Keeffe, TC Brodnicki, B Fancke, D … - International immunology, 2005 - Jpn Soc Immunol
A dendritic cell (DC) imbalance with a marked deficiency in CD4 – 8 + DC
occurs in non-obese diabetic (NOD) mice, a model of human autoimmune diabetes
mellitus. Using a NOD congenic mouse strain, we find that this CD4 – 8 + ...
Cited by 12 - Related articles - All 5 versions

Prevention of Type 1 Diabetes with Major Histocompatibility Complex–Compatible and …

- shouxi.net
GF Beilhack, RR Landa, MA Masek, JA … - Diabetes, 2005 - Am Diabetes Assoc
Progression to hyperglycemia in young nonobese diabetic (NOD) mice is blocked by
the transplantation of hematopoietic cells mismatched at the major
histocompatibility complex (MHC). Because the NOD MHC class II allele, IA ...
Cited by 10 - Related articles - All 5 versions

Preconditioning of NOD mice with anti-CD8 mAb and costimulatory blockade enhances …

- hematologylibrary.org
ST Ildstad, PM Chilton, H Xu, MA Domenick, … - Blood, 2005 - bloodjournal.hematologylibrary.org
Bone marrow transplantation blocks diabetes pathogenesis and reverses
autoimmunity in nonobese diabetic (NOD) mice. However, there is a greater
barrier to engraftment in the context of autoimmunity. In the present ...
Cited by 10 - Related articles - All 5 versions

Flt3-ligand-mobilized peripheral blood, but not Flt3-ligand-expanded bone marrow, …

- alphamedpress.org
Y Huang, M Kucia, F Rezzoug, J Ratajczak, MK … - Stem Cells, 2006 - AlphaMed Press
Facilitating cells (CD8 + /TCR – ) (FCs) enhance engraftment of limiting
numbers of hematopoietic stem cells (HSCs). The primary component of FCs is
precursor-plasmacytoid dendritic cells (p-preDCs), a tolerogenic cell ...
Cited by 6 - Related articles - BL Direct - All 6 versions

The Role of Toll-Like Receptor Pathways in the Mechanism of Type 1 Diabetes


E Lien, D Zipris - Current Molecular Medicine, 2009 - ingentaconnect.com
1 Department of Medicine, University of Massachusetts Medical School, Worcester,
MA 01655, USA 2 Department of Pediatrics, Barbara Davis Center for Childhood
Diabetes, University of Colorado, Aurora, CO 80045, USA Abstract: Toll-like ...
Cited by 5 - Related articles - All 2 versions

Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit …

- jimmunol.org
DV Serreze, MA Osborne, YG Chen, HD … - The Journal of Immunology, 2006 - Am Assoc Immnol
In both humans and NOD mice, particular combinations of MHC genes provide the
primary risk factor for development of the autoreactive T cell responses causing
type 1 diabetes (T1D). Conversely, other MHC variants can confer dominant ...
Cited by 5 - Related articles - BL Direct - All 7 versions

Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes …


JS Allen, K Pang, A Skowera, R Ellis, C … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—The balance of blood dendritic cells was profoundly disturbed at
diabetes diagnosis, with a significantly elevated proportion of plasmacytoid and
reduction of myeloid cells compared with control subjects. Dendritic cell ...
Cited by 6 - Related articles - All 3 versions

Low-dose radiation and its clinical implications: diabetes


GJ Wang, XK Li, K Sakai - Human & Experimental Toxicology, 2008 - het.sagepub.com
*Correspondence: Lu Cai, Department of Medicine, Pharmacology and Toxicology,
and Radiation Oncology, University of Louisville, 511 South Floyd Street, MDR
533, Louisville, KY 40202, USA. E-mail: lcai1@hotmail.com
Cited by 5 - Related articles - BL Direct - All 3 versions


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