L Strizzi, C Bianco, N Normanno, D Salomon - Oncogene, 2005 - nature.com It is increasingly evident that genes known to perform critical roles during early
embryogenesis, particularly during stem cell renewal, pluripotentiality and survival, are also expressed
during the development of cancer. In this regard, oncogenesis may be considered as the ... Cited by 53 - Related articles - BL Direct - All 3 versions
- ►biologists.org EB Harmon, AA Apelqvist, NG Smart, X Gu, DH … - Development, 2004 - dev.biologists.org Identification of endogenous signals that regulate expansion and maturation of organ-specific
progenitor cells is a major goal in studies of organ development. Here we provide evidence that
growth differentiation factor 11 (GDF11), a member of the TGF-ß ligand family, governs ... Cited by 49 - Related articles - All 4 versions
- ►jbc.org H Hua, YQ Zhang, S Dabernat, M Kritzik, D Dietz, L … - Journal of Biological …, 2006 - ASBMB Inhibitor of DNA binding (Id) proteins bind to and inhibit the function of basic helix-loop-helix
(bHLH) transcription factors including those that regulate pancreatic development.
Moreover, bone morphogenetic proteins (BMPs) regulate the expression of Ids. We ... Cited by 27 - Related articles - BL Direct - All 7 versions
Y Zhang, M Kritzik, N Sarvetnick - Journal of Cellular and …, 2005 - interscience.wiley.com Pancreatic islet transplantation represents an attrative approach for the treatment of
diabetes. However, the limited availability of donor islets has largely hampered this
approach. In this respect, the use of alternative sources of islets such as the ex vivo ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►alphamedpress.org I Serafimidis, I Rakatzi, V Episkopou, M Gouti, A … - Stem Cells, 2008 - AlphaMed Press The delineation of regulatory networks involved in early endocrine pancreas specification will
play a crucial role in directing the differentiation of embryonic stem cells toward the mature phenotype
of β cells for cell therapy of type 1 diabetes. The transcription factor Ngn3 is required for ... Cited by 17 - Related articles - BL Direct - All 6 versions
M Banerjee, M Kanitkar, RR … - The Review of Diabetic …, 2005 - pubmedcentral.nih.gov The phenomenon of pancreatic regeneration in mammals has been well documented. It has
been shown that pancreatic tissue is able to regenerate in several species of mammal after surgical
insult. This tissue is also known to have the potential to maintain or increase its β-cell ... Cited by 12 - Related articles - All 5 versions
- ►fasebj.org M Eijken, S Swagemakers, M Koedam, C Steenbergen, … - The FASEB Journal, 2007 - FASEB Bone quality is an important determinant of osteoporosis, and proper osteoblast differentiation
plays an important role in the control and maintenance of bone quality. We investigated the impact
of activin signaling on human osteoblast differentiation, extracellular matrix formation, and ... Cited by 10 - Related articles - BL Direct - All 5 versions
O Andersson, M Korach-Andre, E … - Proceedings of the …, 2008 - National Acad Sciences Growth/differentiation factor 3 (GDF3) is highly expressed in adipose tissue, and previous overexpression
experiments in mice have suggested that it may act as an adipogenic factor under conditions
of high lipid load. GDF3 has been shown to signal via the activin receptor ALK4 during ... Cited by 6 - Related articles - BL Direct - All 7 versions
- ►alphamedpress.org JP Chute, GG Muramoto, HK Dressman, G Wolfe, NJ … - Stem Cells, 2006 - AlphaMed Press Recent progress has been made in the identification of the osteoblastic cellular niche for hematopoietic
stem cells (HSCs) within the bone marrow (BM). Attempts to identify the soluble factors that regulate
HSC self-renewal have been less successful. We have demonstrated that primary human ... Cited by 5 - Related articles - BL Direct - All 10 versions
- ►physiology.org DM Simeone, L Zhang, MK Treutelaar, L … - American Journal of …, 2006 - Am Physiological Soc To investigate the role of transforming growth factor (TGF)- family signaling in the adult
pancreas, a transgenic mouse (E-dnSmad4) was created that expresses a dominant-negative
Smad4 protein driven by a fragment of the elastase promoter. Although E-dnSmad4 mice ... Cited by 5 - Related articles - BL Direct - All 5 versions
