- ►endojournals.org R Granata, F Settanni, L Biancone, L Trovato, R Nano, … - Endocrinology, 2007 - Endocrine Soc Among its pleiotropic actions, ghrelin modulates insulin secretion and glucose metabolism. Herein
we investigated the role of ghrelin in pancreatic ß-cell proliferation and apoptosis induced by
serum starvation or interferon (IFN)- /TNF- , whose synergism is a major cause for ß-cell ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►jbc.org EB Hammar, JC Irminger, K Rickenbach, G … - Journal of Biological …, 2005 - ASBMB Laminin-5-rich extracellular matrix derived from 804G cells (804G-ECM) engages 1 integrins
to induce spreading, improve glucose-stimulated insulin secretion (GSIS), and increase survival
of pancreatic beta cells. The present study examines whether 804G-ECM activates the ... Cited by 39 - Related articles - BL Direct - All 5 versions
G Parnaud, D Bosco, T Berney, F Pattou, J Kerr-Conte, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis The aim of the study was to determine whether purified beta cells can
replicate in vitro and whether this is enhanced by extracellular matrix (ECM) and growth
factors. Methods Human beta cells were purified by FACS by virtue of their high zinc ... Cited by 38 - Related articles - BL Direct - All 3 versions
N Weinberg, L Ouziel-Yahalom, S Knoller, S Efrat, Y … - Diabetes, 2007 - Am Diabetes Assoc Understanding and manipulating pancreatic β-cell proliferation is a major challenge for pancreas
biology and diabetes therapy. Recent studies have raised the possibility that human β-cells can
undergo dedifferentiation and give rise to highly proliferative mesenchymal cells, which ... Cited by 37 - Related articles - BL Direct - All 5 versions
NK Yashpal, J Li, MB Wheeler, R Wang - Endocrinology, 2005 - Endocrine Soc The integrin receptors link to extracellular matrix proteins and exert a dynamic role in development
by providing the physical basis for cell adhesion and controlling cell growth. In the present
study, we examined changes in the expression of ß1 integrins and its associated ... Cited by 26 - Related articles - All 5 versions
- ►diabetesjournals.org R Wang, J Li, K Lyte, NK Yashpal, F Fellows, CG … - Diabetes, 2005 - Am Diabetes Assoc The integrin receptors play a major role in tissue morphogenesis and homeostasis by regulating
cell interactions with extracellular matrix proteins. We have examined the expression pattern
of integrin subunits in the human fetal pancreas (8–20 weeks fetal age) and the relevance ... Cited by 23 - Related articles - All 4 versions
LM Weber, KN Hayda, K Haskins, KS Anseth - Biomaterials, 2007 - Elsevier The influence of matrix-derived adhesive peptide sequences on encapsulated β-cell survival
and glucose-stimulated insulin release was explored by covalently incorporating synthetic peptide
sequences within a model encapsulation environment. Photopolymerized poly(ethylene ... Cited by 23 - Related articles - All 4 versions
- ►diabetesjournals.org G Parnaud, E Hammar, DG Rouiller, M Armanet, PA … - Diabetes, 2006 - Am Diabetes Assoc When attached on a matrix produced by a rat bladder carcinoma cell line (804G matrix), rat pancreatic
β-cells spread in response to glucose and secrete more insulin compared with cells attached
on poly-l-lysine. The aim of this study was to determine whether laminin-5 and its ... Cited by 22 - Related articles - BL Direct - All 5 versions
- ►endojournals.org MY Donath, J Storling, LA Berchtold, N Billestrup, T … - Endocrine …, 2008 - Endocrine Soc The tale of cytokines and the β-cell is a long story, starting with in vitro discovery in 1984, evolving
via descriptive and phenomenological studies to detailed mapping of the signalling
pathways, gene- and protein expression patterns, molecular and biochemical effector ... Cited by 21 - Related articles - BL Direct - All 6 versions
JG Lees, SA Lim, T Croll, G Williams, S Lui, J … - Regenerative …, 2007 - Future Medicine Figure 1.3D cell culturing and transplantation procedure. ... (A) Alkaline phosphatase staining
of hESC colonies. (B)Stage-specific embryonic antigen-4 immunostaining of hESC colony.
(C–D) Scanning electron microscopy (SEM) images of unseeded PLGA scaffolds. (E) ... Cited by 17 - Related articles - BL Direct - All 4 versions
