- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ... Cited by 97 - Related articles - BL Direct - All 5 versions
T Yasukawa, E Tokunaga, H Ota, H Sugita, … - Journal of Biological Chemistry, 2005 - ASBMB Inducible nitric-oxide synthase (iNOS) has been implicated in many human
diseases including insulin resistance. However, how iNOS causes or exacerbates
insulin resistance remains largely unknown. Protein S-nitrosylation is now ... Cited by 55 - Related articles - All 5 versions
- ►ahajournals.org E Nisoli, E Clementi, MO Carruba, S Moncada - Circulation research, 2007 - Am Heart Assoc The metabolic syndrome is a group of risk factors of metabolic origin that are
accompanied by increased risk for type 2 diabetes mellitus and cardiovascular
disease. These risk factors include atherogenic dyslipidemia, elevated ... Cited by 45 - Related articles - All 6 versions
S Wakino, K Hayashi, S Tatematsu, K … - Hypertension Research, 2005 - nature.com Peroxisome proliferator activated receptor- (PPAR ) ligands increase nitric
oxide (NO) production and reduce systemic blood pressure. Asymmetric
dimethylarginine (ADMA) is an endogenous nitric oxide synthase (NOS) ... Cited by 46 - Related articles - All 4 versions
- ►diabetesjournals.org JE Ayala, DP Bracy, OP McGuinness, DH … - Diabetes, 2006 - Am Diabetes Assoc Despite increased use of the hyperinsulinemic-euglycemic clamp to study insulin
action in mice, the effects of experimental parameters on the results obtained
have not been addressed. In our studies, we determined the influences of ... Cited by 40 - Related articles - BL Direct - All 7 versions
V de Fourmestraux, H Neubauer, C Poussin, P … - Journal of Biological Chemistry, 2004 - ASBMB Genetically homogenous C57Bl/6 mice display differential metabolic adaptation
when fed a high fat diet for 9 months. Most become obese and diabetic, but a
significant fraction remains lean and diabetic or lean and non-diabetic. ... Cited by 39 - Related articles - BL Direct - All 4 versions
PH Groop, C Forsblom, MC Thomas - Nature clinical practice. Endocrinology & metabolism, 2005 - ncbi.nlm.nih.gov Resistance to the actions of insulin is strongly associated with the
microvascular complications of diabetes. To the extent that insulin resistance
leads to hyperglycemia, dyslipidemia and hypertension, this association is ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►physiology.org LJ Mullins, MA Bailey, JJ Mullins - Physiological reviews, 2006 - Am Physiological Soc In this review, we outline the application and contribution of transgenic
technology to establishing the genetic basis of blood pressure regulation and
its dysfunction. Apart from a small number of examples where high blood ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►nih.gov DN Atochin, A Wang, VWT Liu, JD Critchlow, … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig NO plays critical roles in vascular function. We show that modulation of the
eNOS serine 1179 (S1179) phosphorylation site affects vascular reactivity and
determines stroke size in vivo. Transgenic mice expressing only a ... Cited by 23 - Related articles - BL Direct - All 8 versions
