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Scholar Results 1 - 10 of about 14 citing Jackson: Polymorphic variations in the neurogenic differentiation-1, neurogenin-3, and hepatocyte.... (0.15 sec) 

Combining information from common type 2 diabetes risk polymorphisms improves disease …


MN Weedon, MI McCarthy, G Hitman, M Walker, … - PLoS Med, 2006 - medicine.plosjournals.org
Three common variants (Lys23 of KCNJ11, Pro12 of PPARG, and the T allele at
rs7903146 of TCF7L2) have been shown to predispose to type 2 diabetes mellitus
across many large studies. Risk allele frequencies ranged from 0.30 to 0.88 ...
Cited by 97 - Related articles - Cached - All 15 versions

Association of common variation in the HNF1α gene region with risk of type 2 diabetes

- diabetesjournals.org
W Winckler, NP Burtt, J Holmkvist, C Cervin, … - Diabetes, 2005 - Am Diabetes Assoc
It is currently unclear how often genes that are mutated to cause rare,
early-onset monogenic forms of disease also harbor common variants that
contribute to the more typical polygenic form of each disease. The gene for ...
Cited by 46 - Related articles - BL Direct - All 6 versions

A large-scale association analysis of common variation of the HNF1α gene with type 2 …

- shouxi.net
MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2005 - Am Diabetes Assoc
HNF1α (TCF1) is a key transcription factor that is essential for pancreatic
β-cell development and function. Rare mutations of HNF1α cause maturity-onset
diabetes of the young. A common variant, G319S, private to the Oji-Cree ...
Cited by 38 - Related articles - BL Direct - All 7 versions

A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor …

- Free from Publisher
S Anuradha, V Radha, R Deepa, T Hansen, B … - Diabetes care, 2005 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Genotyping of Ala98Val was done by the
PCR–restriction fragment–length polymorphism method in the following groups:
1) MODY, defined as non–insulin-dependent diabetes (age at onset <25 ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis


FK Kavvoura, JPA Ioannidis - Human genetics, 2005 - Springer
Abstract A meta-analysis assessed whether the Ala45Thr polymorphism of the
neurogenic differentia- tion 1 (NEUROD1) gene is associated with increased risk
of diabetes mellitus type 1 (T1D) or type 2 (T2D). Fourteen case-control ...
Cited by 14 - Related articles - All 4 versions

Mutations in GCK and HNF-1α explain the majority of cases with clinical diagnosis of MODY …


I Estalella, I Rica, GP de Nanclares, JR … - Clinical Endocrinology, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 11 - Related articles - BL Direct - All 3 versions

IRS1, KCNJ11, PPARgamma2 and HNF-1alpha: do amino acid polymorphisms in these …


A Johansen, DP Jensen, R Bergholdt, HB … - Diabetes, Obesity and Metabolism, 2006 - interscience.wiley.com
Aims: Type 1 diabetes mellitus (T1DM) is a chronic disorder primarily triggered
by environmental and immunological factors in genetically susceptible
individuals. Despite the fact that there are indications of common ...
Cited by 8 - Related articles - All 2 versions

Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or …


L Liu, W Jia, T Zheng, M Li, H Lu, K Xiang - Molecular and cellular biochemistry, 2006 - Springer
Page 1. Molecular and Cellular Biochemistry 290: 199–204, 2006. DOI:
10.1007/s11010-006-9217-4 c g Springer 2006 Ala45Thr variation ...
Cited by 3 - Related articles - BL Direct - All 5 versions

[PDF] Association of A Common Haplotype of Hepatocyte Nuclear Factor 1alpha With Type 2 …


C Wang, C Hu, R Zhang, Q Fang, X Ma, W Jia, … - BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2007 - besjournal.com
Objective To analyze the association of variants of hepatocyte nuclear
factor-1α (HNF-1α) gene with type 2 diabetes in Chinese population. Methods In
152 unrelated type 2 diabetes patients and 93 unrelated controls, eleven ...
Cited by 1 - Related articles - View as HTML - BL Direct - All 2 versions

Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes


JF Louet, SB Smith, JF Gautier, M Molokhia, … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com
Ketosis-prone diabetes (KPD) is a phenotypically defined form of diabetes
characterized by male predominance and severe insulin deficiency. Neurogenin3
(NGN3) is a proendocrine gene, which is essential for the fate of ...
Cited by 1 - Related articles - All 2 versions


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