MN Weedon, MI McCarthy, G Hitman, M Walker, … - PLoS Med, 2006 - medicine.plosjournals.org Three common variants (Lys23 of KCNJ11, Pro12 of PPARG, and the T allele at
rs7903146 of TCF7L2) have been shown to predispose to type 2 diabetes mellitus
across many large studies. Risk allele frequencies ranged from 0.30 to 0.88 ... Cited by 97 - Related articles - Cached - All 15 versions
- ►diabetesjournals.org W Winckler, NP Burtt, J Holmkvist, C Cervin, … - Diabetes, 2005 - Am Diabetes Assoc It is currently unclear how often genes that are mutated to cause rare,
early-onset monogenic forms of disease also harbor common variants that
contribute to the more typical polygenic form of each disease. The gene for ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►shouxi.net MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2005 - Am Diabetes Assoc HNF1α (TCF1) is a key transcription factor that is essential for pancreatic
β-cell development and function. Rare mutations of HNF1α cause maturity-onset
diabetes of the young. A common variant, G319S, private to the Oji-Cree ... Cited by 38 - Related articles - BL Direct - All 7 versions
- Free from Publisher S Anuradha, V Radha, R Deepa, T Hansen, B … - Diabetes care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Genotyping of Ala98Val was done by the
PCR–restriction fragment–length polymorphism method in the following groups:
1) MODY, defined as non–insulin-dependent diabetes (age at onset <25 ... Cited by 15 - Related articles - BL Direct - All 5 versions
FK Kavvoura, JPA Ioannidis - Human genetics, 2005 - Springer Abstract A meta-analysis assessed whether the Ala45Thr polymorphism of the
neurogenic differentia- tion 1 (NEUROD1) gene is associated with increased risk
of diabetes mellitus type 1 (T1D) or type 2 (T2D). Fourteen case-control ... Cited by 14 - Related articles - All 4 versions
I Estalella, I Rica, GP de Nanclares, JR … - Clinical Endocrinology, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 11 - Related articles - BL Direct - All 3 versions
A Johansen, DP Jensen, R Bergholdt, HB … - Diabetes, Obesity and Metabolism, 2006 - interscience.wiley.com Aims: Type 1 diabetes mellitus (T1DM) is a chronic disorder primarily triggered
by environmental and immunological factors in genetically susceptible
individuals. Despite the fact that there are indications of common ... Cited by 8 - Related articles - All 2 versions
L Liu, W Jia, T Zheng, M Li, H Lu, K Xiang - Molecular and cellular biochemistry, 2006 - Springer Page 1. Molecular and Cellular Biochemistry 290: 199–204, 2006. DOI:
10.1007/s11010-006-9217-4 c g Springer 2006 Ala45Thr variation ... Cited by 3 - Related articles - BL Direct - All 5 versions
C Wang, C Hu, R Zhang, Q Fang, X Ma, W Jia, … - BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2007 - besjournal.com Objective To analyze the association of variants of hepatocyte nuclear
factor-1α (HNF-1α) gene with type 2 diabetes in Chinese population. Methods In
152 unrelated type 2 diabetes patients and 93 unrelated controls, eleven ... Cited by 1 - Related articles - View as HTML - BL Direct - All 2 versions
JF Louet, SB Smith, JF Gautier, M Molokhia, … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com Ketosis-prone diabetes (KPD) is a phenotypically defined form of diabetes
characterized by male predominance and severe insulin deficiency. Neurogenin3
(NGN3) is a proendocrine gene, which is essential for the fate of ... Cited by 1 - Related articles - All 2 versions