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Scholar Results 1 - 10 of about 35 citing Bennett: Variation at the Insulin Gene VNTR (Variable Number Tandem Repeat) Polymorphism.... (0.09 sec) 

Insights from the developing world: thrifty genotypes and thrifty phenotypes

- mcmaster.ca [PDF] 
AM Prentice, P Rayco-Solon, SE … - Proceedings of the …, 2007 - Cambridge Univ Press
Few researchers would dispute that the pandemic of obesity is caused by a profound mismatch
between humanity's present environmental circumstances and those that have moulded evolutionary
selection. This concept was first articulated when gestational diabetes was described as ...
Cited by 52 - Related articles - All 7 versions

Genetic variations and normal fetal growth


DB Dunger, CJ Petry, KK Ong - Horm Res, 2006 - content.karger.com
Size at birth is said to be a highly heritable trait, with an estimated 30-70% of the variability a
result of genetics. Data from family studies may be confounded, however, by potential interactions
between fetal genes and the maternal uterine environment. Overall, the maternal ...
Cited by 45 - Related articles - BL Direct - All 5 versions

Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 …

- nih.gov
RM Freathy, MN Weedon, A Bennett, E Hyppönen, … - The American Journal of …, 2007 - Elsevier
The role of genes in normal birth-weight variation is poorly understood, and it has been suggested
that the genetic component of fetal growth is small. Type 2 diabetes genes may influence birth
weight through maternal genotype, by increasing maternal glycemia in pregnancy, or ...
Cited by 43 - Related articles - BL Direct - All 9 versions

Analysis of multiple data sets reveals no association between the insulin gene …

- endojournals.org
BL Powell, L Haddad, A Bennett, N Gharani, U … - Journal of Clinical …, 2005 - Endocrine Soc
Context: Variation at the insulin gene VNTR (variable number tandem repeat) minisatellite has
been reported to be associated with polycystic ovary syndrome (PCOS), but findings have been
inconsistent and all studies have featured small sample sizes. ... Objective: To gain a ...
Cited by 40 - Related articles - All 5 versions

Comparative Analysis of Insulin Gene Promoters


CW Hay, K Docherty - Diabetes, 2006 - Am Diabetes Assoc
DNA sequences that regulate expression of the insulin gene are located within a region spanning
∼400 bp that flank the transcription start site. This region, the insulin promoter, contains a number
of cis-acting elements that bind transcription factors, some of which are expressed only in ...
Cited by 31 - Related articles - BL Direct - All 9 versions

Hypotheses on the fetal origins of adult diseases: contributions of epidemiological …


VWV Jaddoe, JCM Witteman - European journal of epidemiology, 2006 - Springer
Page 1. REVIEW Hypotheses on the fetal origins of adult diseases: Contributions of
epidemiological studies Vincent WV Jaddoe 1,2 & Jacqueline CM Witteman 1 1 Department of
Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands; ...
Cited by 22 - Related articles - BL Direct - All 5 versions

No association between insulin gene variation and adult metabolic phenotypes in …


A Bennett, U Sovio, A Ruokonen, H Martikainen, A … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 886–891 DOI 10.1007/s00125-005-1737-z ARTICLE A.
Bennett . U. Sovio . A. Ruokonen . H. Martikainen . A. Pouta . S. Taponen . A.-L. Hartikainen .
S. Franks . L. Peltonen . P. Elliott . M.-R. Järvelin . MI McCarthy ...
Cited by 19 - Related articles - All 4 versions

Evidence of genetic regulation of fetal longitudinal growth


B Knight, BM Shields, M Turner, RJ Powell, CS … - Early human …, 2005 - Elsevier
Cited by 15 - Related articles - All 9 versions

Replication of IGF2-INS-TH* 5 haplotype effect on obesity in older men and …


S Rodríguez, TR Gaunt, E Dennison, X Chen, HE … - European Journal of …, 2005 - nature.com
Interindividual variation of the IGF2-INS-TH region influences risk of a variety of diseases and
complex traits. Previous studies identified a haplotype (designated IGF2-INS-TH * 5 and tagged
by allele A of IGF2 ApaI, allele 9 of TH01 and class I alleles of INS VNTR) associated with ...
Cited by 11 - Related articles - BL Direct - All 5 versions

The INS VNTR locus does not associate with smallness for gestational age (SGA) …

- endojournals.org
TA Vu-Hong, E Durand, S Deghmoun, P Boutin, … - Journal of Clinical …, 2006 - Endocrine Soc
Results: Class I INS frequencies were similar in the two groups (70% in AGA; 72% in SGA; P
= 0.42). There was significant effect on mean birth weight in neither SGA (P = 0.99) nor AGA
(P = 0.18). Although the INS VNTR locus did not associate with anomalies of insulin ...
Cited by 9 - Related articles - All 5 versions


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