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Scholar Results 1 - 10 of about 36 citing Gu: Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation.... (0.13 sec) 

[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN WEISNAGEL,
GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE BOUCHARD. The
human obesity gene map: the 2005 update. Obesity. 2006;14: 529–644. This ...
Cited by 330 - Related articles - View as HTML - All 6 versions

[PDF] The human obesity gene map: the 2004 update


L Perusse, T Rankinen, A Zuberi, YC Chagnon … - Obesity research, 2005 - informatik.hu-berlin.de
Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ...
Cited by 210 - Related articles - View as HTML - All 6 versions

Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review …


WQ Qiu, MF Folstein - Neurobiology of aging, 2006 - Elsevier
Clinical and epidemiological studies have found that type 2 diabetes, and
hyperinsulinaemia, increased the risk of developing Alzheimer's disease (AD) in
the elderly. The link between hyperinsulinaemia and AD may be ...
Cited by 88 - Related articles - All 14 versions

Alternative Splicing of Human Insulin-Degrading Enzyme Yields a Novel Isoform with a …


W Farris, MA Leissring, ML Hemming, AY … - Biochemistry, 2005 - pubs.acs.org
Deletion of insulin-degrading enzyme (IDE) in mice causes accumulation of
cerebral amyloid β-protein (Aβ), hyperinsulinemia, and glucose intolerance.
Together with genetic linkage and allelic association of IDE to Alzheimer's ...
Cited by 33 - Related articles - All 5 versions

High-density haplotype structure and association testing of the insulin-degrading enzyme ( …

- diabetesjournals.org
JC Florez, S Wiltshire, CM Agapakis, NP Burtt … - Diabetes, 2006 - Am Diabetes Assoc
The insulin-degrading enzyme is responsible for the intracellular proteolysis of
insulin. Its gene IDE is located on chromosome 10, in an area with suggestive
linkage to type 2 diabetes and related phenotypes. Due to the impact of ...
Cited by 29 - Related articles - BL Direct - All 7 versions

[PDF] Association studies between risk for late-onset Alzheimer's disease and variants in insulin …


P Nowotny, AL Hinrichs, S Smemo, JSK Kauwe, … - American Journal of Medical Genetics Part B, 2005 - biology.wustl.edu
Petra Nowotny,1 Anthony L. Hinrichs,1 Scott Smemo,1 John SK Kauwe,1 Taylor
Maxwell,2 Peter Holmans,9 Marian Hamshere,9 Dragana Turic,4 Luke Jehu,4 Paul
Hollingworth,4 Pamela Moore,4 Leslie Bryden,5 Amanda Myers,5 Lisa M. Doil,6 ...
Cited by 28 - Related articles - View as HTML - BL Direct - All 6 versions

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis …

- jbc.org
H Im, M Manolopoulou, E Malito, Y Shen, J … - Journal of Biological Chemistry, 2007 - ASBMB
Insulin-degrading enzyme (IDE) is a zinc metalloprotease that hydrolyzes
amyloid- (A ) and insulin, which are peptides associated with Alzheimer disease
(AD) and diabetes, respectively. Our previous structural analysis of ...
Cited by 20 - Related articles - All 5 versions

The C-terminal domain of human insulin degrading enzyme is required for dimerization and …


P Li, WL Kuo, M Yousef, MR Rosner, WJ Tang - Biochemical and Biophysical Research …, 2006 - Elsevier
Insulin degrading enzyme (IDE), a zinc metalloprotease, can specifically
recognize and degrade insulin, as well as several amyloidogenic peptides such as
amyloid β (Aβ) and amylin. The disruption of IDE function in rodents ...
Cited by 13 - Related articles - All 4 versions

The impact of family history of diabetes and lifestyle factors on abnormal glucose …


A Hilding, AK Eriksson, EE Agardh, V Grill, A … - Diabetologia, 2006 - Springer
Page 1. ARTICLE The impact of family history of diabetes and lifestyle factors on
abnormal glucose regulation in middle-aged Swedish men and women ...
Cited by 12 - Related articles - All 4 versions


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