MC Gershengorn, AA Hardikar, C Wei, E … - Science, 2004 - sciencemag.org Insulin-expressing beta cells, found in pancreatic islets, are capable of
generating more beta cells even in the adult. We show that fibroblast-like cells
derived from adult human islets donated postmortem proliferate readily in ... Cited by 184 - Related articles - All 11 versions
S Bonner-Weir, GC Weir - Nature biotechnology, 2005 - nature.com Two major initiatives are under way to correct the -cell deficit of diabetes:
one would generate -cells ex vivo that are suitable for transplantation, and the
second would stimulate regeneration of -cells in the pancreas. Studies of ... Cited by 172 - Related articles - All 3 versions
- ►amjpathol.org T Fujikawa, SH Oh, L Pi, HM Hatch, T Shupe, … - American Journal of Pathology, 2005 - ASIP Embryonic stem (ES) cells have been proposed to be a powerful tool in the study
of pancreatic disease, as well as a potential source for cell replacement
therapy in the treatment of diabetes. However, data demonstrating the ... Cited by 138 - Related articles - All 8 versions
- ►physiology.org L Bouwens, I Rooman - Physiological reviews, 2005 - Am Physiological Soc Beta-cell mass regulation represents a critical issue for understanding
diabetes, a disease characterized by a near-absolute (type 1) or relative (type
2) deficiency in the number of pancreatic beta cells. The number of islet ... Cited by 115 - Related articles - BL Direct - All 6 versions
- ►lava.med.br [PDF] - Free from Publisher P Huang, S Li, M Han, Z Xiao, R Yang, ZC … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—At the end of the 3-month follow-up, the main manifestations,
including lower limb pain and ulcers, were significantly improved in the
patients of the transplant group. Their laser Doppler blood perfusion of ... Cited by 106 - Related articles - BL Direct - All 36 versions
- ►slas.ac.cn [PDF] X Xu, J D'Hoker, G Stange, S Bonné, N De … - Cell, 2008 - Elsevier Novel strategies in diabetes therapy would obviously benefit from the use of
beta (β) cell stem/progenitor cells. However, whether or not adult β cell
progenitors exist is one of the most controversial issues in today's ... Cited by 101 - Related articles - All 9 versions
- ►nih.gov M Trucco - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Type 1 diabetes is the result of an autoimmune attack against the
insulin-producing β cells of the endocrine pancreas. Current treatment for
patients with type 1 diabetes typically involves a rigorous and invasive ... Cited by 69 - Related articles - All 9 versions
- ►biologists.org AL Means, IM Meszoely, K Suzuki, Y Miyamoto, … - Development, 2005 - dev.biologists.org Epithelial metaplasia occurs when one predominant cell type in a tissue is
replaced by another, and is frequently associated with an increased risk of
subsequent neoplasia. In both mouse and human pancreas, acinar-to-ductal ... Cited by 68 - Related articles - BL Direct - All 5 versions
CT Jordan - Current opinion in cell biology, 2004 - Elsevier The biology of stem cells and their intrinsic properties are now recognized as
integral to tumor pathogenesis in several types of cancer. This observation has
broad ramifications in the cancer research field and is likely to impact ... Cited by 59 - Related articles - All 3 versions
R Gao, J Ustinov, O Korsgren, T Otonkoski - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The neogenesis of islets from cultured human adult
pancreatic tissue has been reported. The islet progenitors have been thought to
be ductal cells. Since previous experiments have been 'contaminated' by a ... Cited by 43 - Related articles - BL Direct - All 5 versions
