- ►diabetesjournals.org S Freude, L Plum, J Schnitker, U Leeser, M Udelhoven, … - Diabetes, 2005 - Am Diabetes Assoc Cerebral insulin receptors play an important role in regulation of energy homeostasis and development
of neurodegeneration. Accordingly, type 2 diabetes characterized by insulin resistance is associated
with an increased risk of developing Alzheimer's disease. Formation of neurofibrillary ... Cited by 26 - Related articles - BL Direct - All 6 versions
O Tschritter, H Preissl, AM Hennige, M … - Proceedings of the …, 2006 - National Acad Sciences Animal studies have shown that the brain is an insulin-responsive organ and that central nervous
insulin resistance induces obesity and disturbances in glucose metabolism. In humans, insulin
effects in the brain are poorly characterized. We used a magnetoencephalography ... Cited by 23 - Related articles - BL Direct - All 9 versions
C Benedict, M Hallschmid, B Schultes, J Born, … - …, 2007 - content.karger.com Background: Compelling evidence indicates that central nervous insulin enhances learning and
memory and in particular benefits hippocampus-dependent (ie, declarative) memory. Intranasal
administration of insulin provides an effective way of delivering the compound to the ... Cited by 15 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org P Rossetti, F Porcellati, NB Ricci, P Candeloro, P Cioli, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Plasma counterregulatory hormone response to hypoglycemia did not differ between
detemir and human insulin. The glycemic thresholds for adrenergic symptoms were higher with
detemir (51 ± 7.7 mg/dl) versus human insulin (56 ± 7.8 mg/dl) (P = 0.029). However, ... Cited by 7 - Related articles - BL Direct - All 4 versions
L Benedict, CA Nelson, E Schunk, K Sullwold, … - …, 2006 - content.karger.com Insulin receptors are found throughout the brain, particularly in the hippocampus, although the
impact of insulin on memory is unclear. The purpose of this study was to examine the effect of
insulin on event-related potentials in response to a standard memory task and visual ... Cited by 4 - Related articles - BL Direct - All 5 versions
JA Fairley - 2007 - icsl.gatech.edu Submitted to the Faculty of the Division of Graduate ... In Partial Fulfillment of the Requirements
for the Degree of Doctor of Philosophy ... School of Electrical and Computer Engineering Georgia
Institute of Technology Atlanta, GA 30332 ... SECTION 1.2 ORIGIN AND HISTORY OF ... Related articles - View as HTML
O Tschritter, SA Schäfer, J Klett, A Pfäfflin, … - Diabetes, Obesity …, 2009 - interscience.wiley.com Methods:12 healthy subjects [6f/6m, age 32 ± 6 years (mean ± sd), body mass index (BMI) 24.2
± 2.5 kg/m 2 ] underwent a 200-min stepwise hypoglycaemic clamp (45 min steps of 4.4, 3.7,
3.0 and 2.3 mmol/l) with either detemir or human insulin in random order. A bolus of ... Related articles - All 3 versions
M Hallschmid, B Schultes - Diabetologia, 2009 - Springer Abstract Research on functions and signalling pathways of insulin has traditionally focused on
peripheral tissues such as muscle, fat and liver, while the brain was commonly believed to be
insensitive to the effects of this hormone secreted by pancreatic beta cells. However, ... Related articles - All 2 versions
S Freude, K Schilbach, M Schubert - Current Alzheimer Research, 2009 - ingentaconnect.com Abstract: In different clinical studies, an association of type 2 diabetes and Alzheimer's disease
(AD) has been described. However, the underlying mechanisms are still unclear. One explanation
could be that vascular complications of diabetes result in neurodegeneration. ... Related articles - All 2 versions
