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Scholar Results 1 - 10 of about 19 citing Spurlin: Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal.... (0.12 sec) 

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose …


E Oh, BA Spurlin, JE Pessin, DC Thurmond - Diabetes, 2005 - Am Diabetes Assoc
The disruption of Munc18c binding to syntaxin 4 impairs insulin-stimulated GLUT4
vesicle translocation in 3T3L1 adipocytes. To investigate the physiological
function and requirement for Munc18c in the regulation of GLUT4 ...
Cited by 34 - Related articles - All 6 versions

The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis

- jbc.org
E Oh, DC Thurmond - Journal of Biological Chemistry, 2006 - ASBMB
Stimulus-induced tyrosine phosphorylation of Munc18c was investigated as a
potential regulatory mechanism by which the Munc18c-Syntaxin 4 complex can be
dissociated in response to divergent stimuli in multiple cell types. Use of ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Syntaxin 4 Facilitates Biphasic Glucose-Stimulated Insulin Secretion from Pancreatic {beta}- …

- endojournals.org
BA Spurlin, DC Thurmond - Molecular Endocrinology, 2006 - Endocrine Soc
Numerous overexpression studies have recently implicated Syntaxin 4 as an
effector of insulin secretion, although its requirement in insulin granule
exocytosis is unknown. To address this, islets from Syntaxin 4 heterozygous ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Regulation of embryo outgrowth by a morphogenic factor, epimorphin, in the mouse


J Qin, Y Takahashi, K Isuzugawa, M Imai, S … - Molecular Reproduction and Development, 2005 - interscience.wiley.com
Conceptus implantation to the uterine endometrium represents a complex series of
events, including synchronized development of conceptus and uterus through up-
and/or down-regulation of numerous gene products. In a previous study using ...
Cited by 13 - Related articles - All 3 versions

Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased …


JB Hurov, M Huang, LS White, J Lennerz, CS … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Obesity is a major factor central to the development of insulin resistance and
type 2 diabetes. The identification and characterization of genes involved in
regulation of adiposity, insulin sensitivity, and glucose uptake are key to ...
Cited by 12 - Related articles - BL Direct - All 8 versions

Doc2β Is a Novel Munc18c-interacting Partner and Positive Effector of Syntaxin 4-mediated …


B Ke, E Oh, DC Thurmond - Journal of Biological Chemistry, 2007 - ASBMB
The widely expressed Sec/Munc18 (SM) protein Munc18c is required for
SNARE-mediated insulin granule exocytosis from islet beta cells and GLUT4
vesicle exocytosis in skeletal muscle and adipocytes. Although Munc18c ...
Cited by 10 - Related articles - All 5 versions

Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes


C Nevado, AM Valverde, M Benito - Endocrinology, 2006 - Endocrine Soc
The liver plays a major role in the regulation of glucose homoeostasis. Evidence
from liver-specific insulin receptor knockout mice (LIRKO) suggested that
insulin's direct and indirect effects on glucose utilization by the liver ...
Cited by 8 - Related articles - BL Direct - All 4 versions

The trypanosome transcriptome is remodelled during differentiation but displays limited …


VL Koumandou, SKA Natesan, T Sergeenko, … - BMC genomics, 2008 - biomedcentral.com
Trypanosomatids utilise polycistronic transcription for production of the vast
majority of protein-coding mRNAs, which operates in the absence of gene-specific
promoters. Resolution of nascent transcripts by polyadenylation and trans- ...
Cited by 9 - Related articles - Cached - All 7 versions

Robust syntaxin-4 immunoreactivity in mammalian horizontal cell processes

- nih.gov
AA HIRANO, JH BRANDSTĂ„TTER, A VILA, … - Visual neuroscience, 2007 - Cambridge Univ Press
Abstract Horizontal cells mediate inhibitory feed-forward and feedback
communication in the outer retina; however, mechanisms that underlie transmitter
release from mammalian horizontal cells are poorly understood. Toward ...
Cited by 4 - Related articles - BL Direct - All 4 versions

The Tyrosine Phosphorylation of Munc18c Induces a Switch in Binding Specificity from …


JL Jewell, E Oh, SM Bennett, SO Meroueh, … - Journal of Biological Chemistry, 2008 - ASBMB
Glucose-stimulated insulin secretion is mediated by syntaxin 4-based SNARE
(soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein
complexes and the Sec1/Munc18 protein Munc18c. Our laboratory recently ...
Cited by 3 - Related articles - All 4 versions


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