- ►cell.com BB Kahn, T Alquier, D Carling, DG Hardie - Cell metabolism, 2005 - Elsevier The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular energy
status, and recent data demonstrate that it also plays a critical role in systemic energy
balance. AMPK integrates nutritional and hormonal signals in peripheral tissues and the ... Cited by 648 - Related articles - All 11 versions
T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel, G … - Obesity, 2006 - pbrc.edu Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN
WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2005 update. Obesity. 2006;14: ... Cited by 335 - Related articles - View as HTML - All 6 versions
L Perusse, T Rankinen, A Zuberi, YC Chagnon, … - Obesity …, 2005 - informatik.hu-berlin.de Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND
CLAUDE BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ... Cited by 210 - Related articles - View as HTML - All 6 versions
- ►nih.gov YC Long, JR Zierath - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular
metabolism. When activated by a deficit in nutrient status, AMPK stimulates glucose uptake and
lipid oxidation to produce energy, while turning off energy-consuming processes ... Cited by 166 - Related articles - BL Direct - All 9 versions
- ►physoc.org M Daval, F Foufelle, P Ferré - The Journal of Physiology, 2006 - Physiological Soc AMP-activated protein kinase (AMPK) is involved in cellular energy homeostasis. Its functions
have been extensively studied in muscles and liver. AMPK stimulates pathways which increase
energy production (glucose transport, fatty acid oxidation) and switches off pathways ... Cited by 52 - Related articles - BL Direct - All 9 versions
- ►jbc.org A Tzatsos, PN Tsichlis - Journal of Biological Chemistry, 2007 - ASBMB Energy depletion activates AMP-activated protein kinase (AMPK) and inhibits cell growth via
TSC2-dependent suppression of mTORC1 signaling. Long term energy depletion also induces
apoptosis by mechanisms that are not well understood to date. Here we show that AMPK, ... Cited by 32 - Related articles - All 5 versions
- ►physiology.org VW Dolinsky, JRB Dyck - American Journal of Physiology- Heart …, 2006 - Am Physiological Soc The heart is capable of utilizing a variety of substrates to produce the necessary ATP for cardiac
function. AMP-activated protein kinase (AMPK) has emerged as a key regulator of cellular energy
homeostasis and coordinates multiple catabolic and anabolic pathways in the heart. ... Cited by 30 - Related articles - BL Direct - All 3 versions
L Fryer, D Carling - Biochemical Society Transactions, 2005 - bst.portlandpress.com The occurrence of Type II (non-insulin-dependent) diabetes and obesity and their associated
morbidities continue to increase and they are rapidly reaching epidemic proportions. AMPK
(AMP-activated protein kinase) was initially thought of as an intracellular 'fuel gauge' ... Cited by 29 - Related articles - Cached - All 9 versions
P Katajisto, T Vallenius, K Vaahtomeri, N Ekman, L … - BBA-Reviews on Cancer, 2007 - Elsevier Inactivating germline mutations in the LKB1 gene underlie Peutz–Jeghers syndrome characterized
by hamartomatous polyps and an elevated risk for cancer. Recent studies suggest the involvement
of LKB1 also in more common human disorders including diabetes and in a significant ... Cited by 29 - Related articles - All 5 versions
G Schimmack, RA DeFronzo, N Musi - Diabetes Obesity and …, 2006 - pt.wkhealth.com AMP-activated protein kinase (AMPK) is an enzyme that works as a fuel gauge which becomes
activated in situations of energy consumption. AMPK functions to restore cellular ATP levels by
modifying diverse metabolic and cellular pathways. In the skeletal muscle, AMPK is ... Cited by 26 - Related articles - BL Direct - All 5 versions
