- ►pnas.org AW Goldrath, CJ Luckey, R Park, C Benoist, D … - Proceedings of the National Academy of Sciences, 2004 - National Acad Sciences Naïve T cells proliferate independently of cognate antigen when introduced into
lymphopenic hosts. Lymphopenia-induced proliferation depends on low-affinity
MHC/self-peptide complexes and on IL-7. To elucidate the intracellular ... Cited by 74 - Related articles - BL Direct - All 10 versions
- ►jimmunol.org J Taieb, N Chaput, N Schartz, S Roux, S … - The Journal of Immunology, 2006 - Am Assoc Immnol Dendritic cell-derived exosomes (DEX) are nanomeric vesicles harboring
MHC/peptide complexes capable of promoting primary T cell responses and tumor
rejection in the presence of adjuvants. In this study, we show that, in the ... Cited by 55 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org S Brode, T Raine, P Zaccone, A Cooke - The Journal of Immunology, 2006 - Am Assoc Immnol Regulatory T cells (Tregs) have been implicated as key players in immune
tolerance as well as suppression of antitumor responses. The chemotherapeutic
alkylating agent cyclophosphamide (CY) is widely used in the treatment of ... Cited by 42 - Related articles - All 5 versions
- ►nih.gov W Du, FS Wong, MO Li, J Peng, H Qi, RA … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig We have previously isolated insulin-reactive Tregs from diabetic NOD mice
designated 2H6, from which TCR transgenic mice were generated. The T cells from
these 2H6 transgenic mice recognize insulin but have suppressive properties ... Cited by 23 - Related articles - BL Direct - All 8 versions
- ►oxfordjournals.org RJ Boyton, S Davies, C Marden, C Fantino, … - International immunology, 2005 - Jpn Soc Immunol There is much interest in therapeutic manipulation of cytokine responses in
autoimmunity, yet studies in mouse models have sometimes produced conflicting
findings as to the role of particular mediators in disease. Examples ... Cited by 11 - Related articles - BL Direct - All 6 versions
N Martin-Orozco, Y Chung, SH Chang, YH … - Eur. J. Immunol, 2009 - interscience.wiley.com IDDM is characterized by leukocyte invasion to the pancreatic tissues followed
by immune destruction of the islets. Despite the important function of Th17
cells in other autoimmune disease models, their function in IDDM is ... Cited by 11 - Related articles - All 2 versions
- ►bentham.org [PDF] J Zhang, Q Tian, SF Zhou - Current Drug Therapy, 2006 - ingentaconnect.com Abstract: The oxazaphosphorine cyclophosphamide (CPA) and ifosfamide (IFO) are
two commonly used DNA- alkylating agents in cancer chemotherapy. This review
highlights the pharmacokinetics and pharmacodynamics of the two important ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►rupress.org MH Fortier, E Caron, MP Hardy, G Voisin, S … - Journal of Experimental Medicine, 2008 - jem.rupress.org Under steady-state conditions, major histocompatibility complex (MHC) I
molecules are associated with self-peptides that are collectively referred to as
the MHC class I peptide (MIP) repertoire. Very little is known about the ... Cited by 12 - Related articles - BL Direct - All 6 versions
P Hekerman, J Zeidler, S Korfmacher, S … - BMC Molecular Biology, 2007 - biomedcentral.com We have used RINm5F insulinoma cells as a model system for a peripheral target
cell of leptin. Six transcripts encoding inflammation-related proteins were
found to be upregulated by activation of LEPRb, namely lipocalin-2, ... Cited by 8 - Related articles - Cached - All 9 versions
R Planas, A Alba, J Carrillo, MC Puertas, R … - Diabetologia, 2006 - Springer Page 1. ARTICLE Reg (regenerating) gene overexpression in islets from
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