- ►joslinresearch.org [PDF] LJ Scott, KL Mohlke, LL Bonnycastle, CJ … - Science, 2007 - sciencemag.org 333 article(s) on the ISI Web of Science. cited by This article has been ... :
subject collections This article appears in the following ... 2007 by the
American Association for the Advancement of Science; all rights reserved. ... Cited by 766 - Related articles - BL Direct - All 12 versions
… I Reynisdottir, R Benediktsson, T Jonsdottir … - Nature genetics, 2007 - nature.com We conducted a genome-wide association study for type 2 diabetes (T2D) in
Icelandic cases and controls, and we found that a previously described variant
in the transcription factor 7-like 2 gene (TCF7L2) gene conferred the most ... Cited by 316 - Related articles - BL Direct - All 14 versions
- ►endojournals.org B Holst, KL Egerod, E Schild, SP Vickers, S … - Endocrinology, 2007 - Endocrine Soc GPR39 is an orphan member of the ghrelin receptor family that recently was
suggested to be the receptor for obestatin, a peptide derived from the ghrelin
precursor. Here, we compare the effect of obestatin to the effect of Zn 2+ ... Cited by 125 - Related articles - BL Direct - All 4 versions
RJ Cousins, JP Liuzzi, LA Lichten - Journal of Biological Chemistry, 2006 - ASBMB Structural, catalytic, and regulatory functions of zinc in biology continue to
be defined. The number of genes coding for proteins with zinc-binding domains is
conservatively estimated at >3% of the human genome but possibly is as much ... Cited by 101 - Related articles - All 4 versions
- ►wisc.edu [PDF] DJ Eide - BBA-Molecular Cell Research, 2006 - Elsevier Zinc is an essential cofactor required for the structure and function of many
proteins. Studies of the cell biology of zinc date back perhaps to the discovery
of the zinc-binding cytosolic metallothionein (MT) protein by Margoshes and ... Cited by 91 - Related articles - All 6 versions
- ►pnas.org JM Wenzlau, K Juhl, L Yu, O Moua, SA Sarkar … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Type 1 diabetes (T1D) results from progressive loss of pancreatic islet mass
through autoimmunity targeted at a diverse, yet limited, series of molecules
that are expressed in the pancreatic β cell. Identification of these ... Cited by 89 - Related articles - BL Direct - All 6 versions
- ►biologists.org F Chimienti, S Devergnas, F Pattou, F Schuit … - Journal of cell science, 2006 - jcs.biologists.org Insulin-secreting pancreatic beta cells are exceptionally rich in zinc. In these
cells, zinc is required for zinc-insulin crystallization within secretory
vesicles. Secreted zinc has also been proposed to be a paracrine and ... Cited by 49 - Related articles - BL Direct - All 9 versions
H Staiger, F Machicao, N Stefan, O Tschritter, … - PLoS One, 2007 - pubmedcentral.nih.gov Background. Type 2 diabetes arises when insulin resistance-induced compensatory
insulin secretion exhausts. Insulin resistance and/or b-cell dysfunction result
from the interaction of environmental factors (high-caloric diet and ... Cited by 47 - Related articles - All 5 versions
K Kirchhoff, F Machicao, A Haupt, SA Schäfer, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Variation within six novel genetic loci has been
reported to confer risk of type 2 diabetes and may be associated with beta cell
dysfunction. We investigated whether these polymorphisms are also ... Cited by 38 - Related articles - BL Direct - All 3 versions
T Suzuki, K Ishihara, H Migaki, W Matsuura, … - Journal of Biological Chemistry, 2005 - ASBMB Numerous proteins are properly folded by binding with zinc during their
itinerary in the biosynthetic-secretory pathway. Several transporters have been
implicated in the zinc entry into secretory compartments from cytosol, but ... Cited by 39 - Related articles - All 5 versions
