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Scholar Results 1 - 10 of about 29 citing Rudovich: Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide.... (0.11 sec) 

Dipeptidyl peptidase IV (DPP IV) inhibitors: a newly emerging drug class for the treatment of …

- dvdres.com [PDF] 
BD Green, PR Flatt, CJ Bailey - Diabetes & Vascular Disease Research, 2006 - dvr.sagepub.com
Abstract I nhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) provide a
strategy for the treatment of type 2 dia- betes. DPP IV rapidly inactivates the
incretin hor- mones glucagon-like peptide-1 (GLP-1) and glucose- dependent ...
Cited by 40 - Related articles - BL Direct - All 9 versions

Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist …


N Irwin, PL McClean, FPM O'Harte, VA Gault, P … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP)
receptor action is reported to protect against obesity and associated metabolic
abnormalities. The aim of this study was to use prediabetic ob/ob mice to ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Incretin hormone mimetics and analogues in diabetes therapeutics

- qub.ac.uk [PDF] 
BD Green, PR Flatt - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier
The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are physiological gut peptides with
insulin-releasing and extrapancreatic glucoregulatory actions. Incretin ...
Cited by 29 - Related articles - All 17 versions

Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide …


JJ Meier, B Gallwitz, M Askenas, K Vollmer, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 1872–1881 DOI 10.1007/s00125-005-1863-7 ARTICLE
JJ Meier . B. Gallwitz . M. Askenas . K. Vollmer . CF Deacon . JJ Holst . ...
Cited by 25 - Related articles - BL Direct - All 3 versions

Inhibition of dipeptidyl peptidase IV activity as a therapy of type 2 diabetes

- qub.ac.uk [PDF] 
BD Green, PR Flatt, CJ Bailey - Expert Opin. Emerging Drugs, 2006 - informahealthcare.com
Dipeptidyl peptidase IV (DPP IV) is a ubiquitous, multifunctional, serine
protease enzyme and receptor with roles in the control of endocrine and immune
function, cell metabolism, growth and adhesion. As an enzyme, DPP IV ...
Cited by 17 - Related articles - BL Direct - All 6 versions

Review: Development and therapeutic potential of incretin hormone analogues for type 2 …

- qub.ac.uk [PDF] 
BD Green, N Irwin, VA Gault, FP O'Harte, PR … - The British Journal of Diabetes & Vascular Disease, 2005 - dvd.sagepub.com
Abstract T he rising prevalence of type 2 diabetes and increasing burden of
diabetic complications requires new approaches to diabetes therapy. An
encouraging new approach for development of future anti-diabetic drugs is ...
Cited by 14 - Related articles - All 7 versions

Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid …

- qub.ac.uk [PDF] 
N Irwin, GC Clarke, BD Green, B Greer, P … - Biochemical pharmacology, 2006 - Elsevier
Glucose dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone
with therapeutic potential for type 2 diabetes due to its insulin-releasing and
antihyperglycaemic actions. However, development of GIP-based therapies is ...
Cited by 11 - Related articles - All 5 versions

[PDF] Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes


PR Flatt, CJ Bailey, BD Green - Front Biosci, 2008 - qub.ac.uk
1. Abstract 2. Introduction 3. DPP IV and related enzymes 3.1. DPP IV (EC
3.4.14.5) 3.2. Dipeptidyl peptidase II (DPP II) 3.3. Dipeptidyl peptidase 8 (DPP
8) and dipeptidyl peptidase 9 (DPP 9) 3.4. Fibroblast Activation protein ...
Cited by 9 - Related articles - View as HTML - All 2 versions

Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by …

- physiology.org
JJ Meier, JJ Holst, WE Schmidt, MA Nauck - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Changes in hepatic insulin clearance can occur after oral glucose or meal
ingestion. This has been attributed to the secretion and action of gastric
inhibitory polypeptide (GIP) and glucagon-like peptide (GLP)–1. Given the ...
Cited by 7 - Related articles - BL Direct - All 5 versions

C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits …


VA Gault, BD Kerr, N Irwin, PR Flatt - Biochemical Pharmacology, 2008 - Elsevier
Glucose-dependent insulinotropic polypeptide has been proposed as a potential
therapeutic for type 2 diabetes, however, efforts to bring forward this drug
have been hindered due to its short circulating half-life. We have adopted ...
Cited by 6 - Related articles - All 4 versions


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