TS Kern - Exp Diabetes Res, 2007 - hindawi.com Diabetes causes metabolic and physiologic abnormalities in the retina, and these changes suggest
a role for inflammation in the development of diabetic retinopathy. These changes include upregulation
of iNOS, COX-2, ICAM-1, caspase 1, VEGF, and NF-κB, increased production of nitric ... Cited by 34 - Related articles - View as HTML - All 12 versions
- ►iovs.org MJ Gastinger, RSJ Singh, AJ Barber - Investigative ophthalmology & visual …, 2006 - ARVO RESULTS. The number of TUNEL-positive nuclei increased from 29 ± 4 in controls to 72 ± 9
in the STZ-diabetic rat retinas after only 2 weeks of diabetes. In rats, CM-1-immunoreactive
(IR) cells were found primarily in the inner nuclear and ganglion cell layers after 2, 8, and ... Cited by 18 - Related articles - BL Direct - All 4 versions
EL Fletcher, JA Phipps, MM Ward, T … - Current …, 2007 - ingentaconnect.com Abstract: Diabetes is known to cause significant alterations in the retinal vasculature. Indeed,
diabetic retinopathy is the leading cause of blindness in those of working age. Considerable
evidence is emerging that indicates that retinal neurons are also altered during diabetes. ... Cited by 15 - Related articles - BL Direct - All 3 versions
T Oshitari, S Roy - Neuroscience letters, 2005 - Elsevier This study was performed to determine whether early diabetes accelerates retinal neuronal cell
death and inhibits neurite regeneration. Five of ten rats were rendered diabetic with streptozotocin
injection. After 3 weeks of diabetes, retinas were isolated and retinal explants were ... Cited by 14 - Related articles - All 3 versions
CJ Layton, S Becker, NN Osborne - Mol Vis, 2006 - molvis.org The traditional view of diabetic retinopathy, based on oph- thalmoscopic observations, is of a
microangiopathic compli- cation associated with diabetes beginning after a long period of the
disease [1]. However, more recent investigations into the effect of diabetes on retinal ... Cited by 12 - Related articles - View as HTML - All 3 versions
A Bastaki - INTERNATIONAL JOURNAL OF DIABETES AND …, 2005 - ijod.uaeu.ac.ae Abstract Diabetes mellitus (DM) is a metabolic disorder resulting from a defect in insulin
secretion, insulin action, or both. Insulin deficiency in turn leads to chronic hyperglycaemia with
disturbances of carbohydrate, fat and protein metabolism. It is the most common ... Cited by 7 - Related articles - View as HTML - BL Direct - All 2 versions
T Oshitari, N Hata, S Yamamoto - Vascular Health and Risk …, 2008 - pubmedcentral.nih.gov Endoplasmic reticulum (ER) stress is involved in the pathogenesis of several diseases including
Alzheimer disease and Parkinson disease. Many recent studies have shown that ER stress is
related to the pathogenesis of diabetes mellitus, and with the death of pancreatic β-cells, ... Cited by 7 - Related articles - BL Direct - All 8 versions
TS Kern, AJ Barber - The Journal of Physiology, 2008 - pubmedcentral.nih.gov Diabetic retinopathy has long been recognized as a vascular disease that develops in most
patients, and it was believed that the visual dysfunction that develops in some diabetics was
due to the vascular lesions used to characterize the disease. It is becoming increasingly ... Cited by 7 - Related articles - All 7 versions
- ►iovs.org KN Volpert, A Rothermel, PG Layer - Investigative Ophthalmology & Visual …, 2007 - ARVO RESULTS. Supplementation with GDNF accelerated rhodopsin mRNA expression and sustained
it at an increased level, in contrast to untreated control subjects, where rhodopsin mRNA levels
were lower and unmaintained. Expression of red, green, blue, and violet opsins were ... Cited by 6 - Related articles - BL Direct - All 5 versions
M Amano, K Suemaru, R Cui, Y Umeda, B Li, … - Acta Medica …, 2007 - lib.okayama-u.ac.jp Several epidemiological and clinical studies have indicated that the prevalence of psychiatric
disorders is higher in diabetic patients than in the general population. In the present studies,
we examined the behavioral changes in streptozotocin-induced diabetic rats, and ... Cited by 5 - Related articles - View as HTML - BL Direct - All 4 versions
