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Scholar Results 1 - 10 of about 23 citing Guidry: Changes in IGF activities in human diabetic vitreous. (0.12 sec) 

The role of growth hormone, insulin-like growth factor and somatostatin in diabetic …


JL Wilkinson-Berka, C Wraight, G Werther - Current medicinal chemistry, 2006 - ingentaconnect.com
Abstract: Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are
implicated in the aberrant cell growth and pathological neovascularization that
characterises proliferative diabetic retinopathy. While serum levels of ...
Cited by 25 - Related articles - BL Direct - All 4 versions

IGF2: Epigenetic regulation and role in development and disease


W Chao, PA D'Amore - Cytokine & growth factor reviews, 2008 - pubmedcentral.nih.gov
Insulin-like growth factor II (IGF2) is perhaps the most intricately regulated
of all growth factors characterized to date. Its gene is imprinted—only one
allele is active, depending on parental origin—and this pattern of ...
Cited by 22 - Related articles - All 9 versions

[PDF] The effect of insulin and glucose levels on retinal glial cell activation and pigment epithelium …


CJ Layton, S Becker, NN Osborne - Mol Vis, 2006 - molvis.org
The traditional view of diabetic retinopathy, based on oph- thalmoscopic
observations, is of a microangiopathic compli- cation associated with diabetes
beginning after a long period of the disease [1]. However, more recent ...
Cited by 12 - Related articles - View as HTML - All 3 versions

Differential expression of vitreous proteins in proliferative diabetic retinopathy


SJ Kim, S Kim, J Park, HK Lee, KS Park, HG … - Current Eye Research, 2006 - informahealthcare.com
Purpose: To identify vitreous proteins that were differentially expressed in
patients suffering from proliferative diabetic retinopathy with active
neovascularization. Methods: The vitreous samples of 15 active ...
Cited by 7 - Related articles - BL Direct - All 7 versions

The insulin-like growth factor system modulates retinal pigment epithelial cell tractional …

- iovs.org
S Mukherjee, C Guidry - Investigative Ophthalmology & Visual Science, 2007 - ARVO
RESULTS. RPE cells generated tractional forces in response to IGF-I and -II with
IGF-I being the more potent stimulus. Differential RPE responses to R 3 IGF-I
reflected minor amounts of endogenous IGFBP production. IGFBP-2, -3, and -5 ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Positive association of pigment epithelium-derived factor with total antioxidant capacity in the …


M Yokoi, S Yamagishi, A Saito, Y Yoshida, T … - British Medical Journal, 2007 - bjo.bmj.com
Background: Pigment epithelium-derived factor (PEDF), a glycoprotein with potent
neuronal differentiating activity, was recently found to inhibit advanced
glycation end product (AGE)-induced retinal hyperpermeability and ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Muller cell production of insulin-like growth factor-binding proteins in vitro: modulation with …

- iovs.org
JL King, C Guidry - Investigative ophthalmology & visual science, 2004 - ARVO
PURPOSE. Müller cells are present in diabetic fibrocontractive ocular tissues
and generate tractional forces in response to insulin-like growth factors.
Recent studies indicate that diabetes-associated increases in vitreous ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Profiling of vitreous proteomes from proliferative diabetic retinopathy and nondiabetic …


T Kim, SJ Kim, K Kim, UB Kang, C Lee, KS … - Proteomics, 2007 - interscience.wiley.com
Diabetes can lead to serious microvascular complications like proliferative
diabetic retinopathy (PDR), which is the leading cause of blindness in adults.
The proteomic changes that occur during PDR cannot be measured in the human ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Vitreous and Serum Levels of Platelet-Derived Growth Factor and Their Correlation in …


A Praidou, I Klangas, E Papakonstantinou, S … - Current Eye Research, 2009 - informahealthcare.com
Purpose: We investigated possible correlations between vitreous and/or serum
levels of platelet derived growth factor isoforms (PDGF-AA, -AB, -BB) with
parameters associated with proliferative diabetic retinopathy (PDR), and ...
Cited by 2 - Related articles - All 6 versions

Growth hormone is present in the human retina and vitreous fluid


S Harvey, E Parker, I Macdonald, EJ Sanders - Neuroscience Letters, 2009 - Elsevier
Growth factors have been found in vitreous fluid, in which they regulate retinal
function and provide markers of ocular dysfunction. Since growth hormone (GH)
has recently been discovered in the eyes of rodents and embryonic chicks ...
Cited by 2 - Related articles - All 2 versions


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